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dc.contributor.authorMombach, Jose Carlos Merinopt_BR
dc.contributor.authorGlazier, James Alexanderpt_BR
dc.contributor.authorRaphael, Richard C.pt_BR
dc.contributor.authorZajac, Markpt_BR
dc.date.accessioned2014-08-12T02:10:16Zpt_BR
dc.date.issued1995pt_BR
dc.identifier.issn0031-9007pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/100077pt_BR
dc.description.abstractWe study the effect of inhibition of cell-membrane ruffling on cell sorting in experiments and simulations. We use aggregates of neural retinal and pigmented retinal cells obtained from chicken embryos and inhibit membrane ruffling by adding the drug cytochalasin B to the culture medium. Simulations using the large-Q Potts model with differential adhesivity, with the simulation temperature controlling the membrane ruffling amplitude, agree quantitatively with the experimental results for both normal and low fluctuation sorting, providing strong support for the validity of the model. In both cases, inhibition of ruffling prevents large scale cell sorting.en
dc.format.mimetypeapplication/pdf
dc.language.isoengpt_BR
dc.relation.ispartofPhysical Review Letters. Woodbury. Vol. 75, n. 11 (Sept. 1995), p. 2244-2247pt_BR
dc.rightsOpen Accessen
dc.subjectFísica da matéria condensadapt_BR
dc.subjectBiofísicapt_BR
dc.titleQuantitative comparison between differential adhesion models and cell sorting in the presence and absence of fluctuationspt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000084868pt_BR
dc.type.originEstrangeiropt_BR


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