|Título||Vitamin D Insufficiency Is Associated with Lower Physical Function in Patients with Heart Failure and Diabetes
Lopes, Maristela Resch
Ribeiro, Paula Aver Bretanha
Ledur, Priscila dos Santos
Souza, Gabriela Corrêa
Clausell, Nadine Oliveira
Schaan, Beatriz D'Agord
|Abstract||Vitamin D deficiency is frequent among patients with heart failure (HF) and diabetes, disorders associated with exercise intolerance and muscle weakness. This study aims to search for associations between vitamin D sufficiency and physical function indexes in patients with HF and diabetes. A cross-sectional study of 146 HF patients, 39.7% with diabetes, at a Brazilian tertiary outpatient clinic was performed. Patients underwent clinical evaluation, 6-minute walk test (6MWT), handgrip strength, physical activity level (IPAQ), and biochemical evaluations including serum 25-hydroxyvitamin D. Classification was done according to vitamin D status (≥30 ng/dL, sufficient) and presence/absence of diabetes in vitamin sufficient, no diabetes (DS-C, n = 25), vitamin sufficient, diabetes (DS-DM, n = 18), vitamin deficient, no diabetes (DD-C, n = 63), and vitamin deficient, diabetes (DD-DM, n = 40). Patients age was 55.4 ± 8 yrs; 70.5% had vitamin D deficiency. Clinical characteristics were similar among groups. Total time expended in physical activity was similar among groups (P = 0.26). DS-C covered higher distances in the 6MWT (392 ± 60 m) versus DD-DM (309 ± 116m); P = 0.024. Handgrip strength was similar among groups but tended to lower levels in DD-DM (P = 0.074) even after being adjusted to physical activity (P = 0.069). Vitamin D deficiency can influence physical function in HF diabetic patients.
|Contido em||Journal of Diabetes Research. Nasr City, Cairo : Hindawi Publishing Corporation, -. Volume 2014, Article ID 320930, 9 p.
Complicações do diabetes
Deficiência de vitamina D
Insuficiência cardíaca : Complicações
|Tipo||Artigo de periódico
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