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Cardiovascular risk factors in outpatients with bipolar disorder : a report from the Brazilian Research Network in Bipolar Disorder

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Cardiovascular risk factors in outpatients with bipolar disorder : a report from the Brazilian Research Network in Bipolar Disorder

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Título Cardiovascular risk factors in outpatients with bipolar disorder : a report from the Brazilian Research Network in Bipolar Disorder
Autor Gomes, Fabiano Alves
Almeida, Karla Mathias de
Magalhães, Pedro Vieira da Silva
Caetano, Sheila Cavalcante
Sant’Anna, Marcia Kauer
Lafer, Beny
Kapczinski, Flávio Pereira
Abstract Objective: Bipolar disorder (BD) is associated with significant morbidity and mortality due to comorbid general medical conditions, particularly cardiovascular disease. This study is the first report of the Brazilian Research Network in Bipolar Disorder (BRN-BD) that aims to evaluate the prevalence and clinical correlates of cardiovascular risk factors among Brazilian patients with BD. Methods: A cross-sectional study of 159 patients with DSM-IV BD, 18 years or older, consecutively recruited from the Bipolar Research Program (PROMAN) in Sa˜o Paulo and the Bipolar Disorder Program (PROTAHBI) in Porto Alegre. Clinical, demographic, anthropometric, and metabolic variables were systematically assessed. Results: High rates of smoking (27%), physical inactivity (64.9%), alcohol use disorders (20.8%), elevated fasting glucose (26.4%), diabetes (13.2%), hypertension (38.4%), hypertriglyceridemia (25.8%), low HDL-cholesterol (27.7%), general (38.4%) and abdominal obesity (59.1%) were found in the sample. Male patients were more likely to have alcohol use disorders, diabetes, and hypertriglyceridemia, whereas female patients showed higher prevalence of abdominal obesity. Variables such as medication use pattern, alcohol use disorder, and physical activity were associated with selected cardiovascular risk factors in the multivariable analysis. Conclusion: This report of the BRN-BD provides new data regarding prevalence rates and associated cardiovascular risk factors in Brazilian outpatients with BD. There is a need for increasing both awareness and recognition about metabolic and cardiovascular diseases in this patient population.
Contido em Revista brasileira de psiquiatria (1999). São Paulo. Vol. 35, n. 2 (abr./jun. 2013), p. 126-130
Assunto Comorbidade
Doenças cardiovasculares
Transtorno bipolar
[en] Bipolar disorder
[en] Cardiovascular risk factors
[en] Comorbidity
Origem Nacional
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/111610
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