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In vivo dosimetry of thyroid doses from different irradiated sites in children and adolescents : a cross-sectional study

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In vivo dosimetry of thyroid doses from different irradiated sites in children and adolescents : a cross-sectional study

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Título In vivo dosimetry of thyroid doses from different irradiated sites in children and adolescents : a cross-sectional study
Autor Bonato, Cassiane Cardoso
Dias, Henrique Bregolin
Alves, Michele da Silva
Duarte, Lucas Ost
Dias, Telpo Martins
Dalenogare, Maiara Oliveira
Viegas, Claudio Castelo Branco
Elnecave, Regina Helena
Abstract Background: Scattered radiation can be assessed by in vivo dosimetry. Thyroid tissue is sensitive to radiation, even at doses <10 cGy. This study compared the scattered dose to the thyroid measured by thermoluminescent dosimeters (TLDs) and the estimated one by treatment planning system (TPS). Methods: During radiotherapy to sites other than the thyroid of 16 children and adolescents, seventy-two TLD measurements at the thyroid were compared with TPS estimation. Results: The overall TPS/TLD bias was 1.02 (95% LA 0.05 to 21.09). When bias was stratified by treatment field, the TPS overestimated TLD values at doses <1 cGy and underestimated them at doses >10 cGy. The greatest bias was found in pelvis and abdomen: 15.01 (95% LA 9.16 to 24.61) and 5.12 (95% LA 3.04 to 8.63) respectively. There was good agreement in orbit, head, and spine: bias 1.52 (95% LA 0.48 to 4.79), 0.44 (95% LA 0.11 to 1.82) and 0.83 (0.39 to 1.76) respectively. There was small agreement with broad limits for lung and mediastinum: 1.13 (95% LA 0.03 to 40.90) and 0.39 (95% LA 0.02 to 7.14) respectively. Conclusions: The scattered dose can be measured with TLDs, and TPS algorithms for outside structures should be improved.
Contido em Radiation oncology. London. Vol. 9 (Jan. 2014), 8p.
Assunto Adolescente
Criança
Dosimetria termoluminescente
Glândula tireóide
Radioterapia
[en] Adolescent
[en] Child
[en] Radiotherapy
[en] Thermoluminescent dosimetry
[en] Thyroid gland
Origem Estrangeiro
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/111833
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