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dc.contributor.authorBorghese, Brunopt_BR
dc.contributor.authorChartier, Mélaniept_BR
dc.contributor.authorSouza, Carlos Augusto Bastos dept_BR
dc.contributor.authorSantulli, Pietropt_BR
dc.contributor.authorPillet, Marie-Christine Lafaypt_BR
dc.contributor.authorZiegler, Dominique dept_BR
dc.contributor.authorChapron, Charlespt_BR
dc.date.accessioned2015-11-18T02:38:06Zpt_BR
dc.date.issued2014pt_BR
dc.identifier.issn2314-6141pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/129821pt_BR
dc.description.abstractObjectives.The identification of epidemiological factors increasing the risk of endometriosis could shorten the time to diagnosis. Specific blood groups may be more common in patients with endometriosis. Study Design. We designed a cross-sectional study of 633 Caucasian women living in the same geographic area. Study group included 311 patients with histologically proven endometriosis. Control group included 322 patients without endometriosis as checked during surgery. Frequencies of ABO and Rhesus groups in the study and control groups were compared using univariate and multivariate analyses. Results. We observed a higher proportion of Rh-negativewomen in the study group, as compared to healthy controls.Multivariate analysis showed that Rhnegative women are twice as likely to develop endometriosis (aOR = 1.90; 95% CI: 1.20–2.90). There was no significant difference in ABO group distribution between patients and controls. There was no difference when taking into account either the clinical forms (superficial endometriosis, endometrioma, and deep infiltration endometriosis) or the rAFS stages. Conclusion. Rh-negative women are twice as likely to develop endometriosis. Chromosome 1p, which contains the genes coding for the Rhesus, could also harbor endometriosis susceptibility genes.en
dc.format.mimetypeapplication/pdf
dc.language.isoengpt_BR
dc.relation.ispartofBioMed Research International. New York, NY. Vol. 2014 (2014), ID 618964, [6] p.pt_BR
dc.rightsOpen Accessen
dc.subjectEndometriosept_BR
dc.subjectSistema do grupo sanguíneo ABOpt_BR
dc.subjectSistema do grupo sanguíneo Rh-Hrpt_BR
dc.subjectPredisposição genética para doençapt_BR
dc.titleABO and rhesus blood groups and risk of endometriosis in a French caucasian population of 633 patients living in the same geographic areapt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000977244pt_BR
dc.type.originEstrangeiropt_BR


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