Mostrar registro simples

Influence of a subinhibitory concentration of vancomycin on the in vitro expression of virulence-related genes in the vancomycin-resistant enterococcus faecalis

dc.contributor.authorMoura, Tiane Martin dept_BR
dc.contributor.authorCampos, Fabrício Souzapt_BR
dc.contributor.authorCaierão, Julianapt_BR
dc.contributor.authorRoehe, Paulo Michelpt_BR
dc.contributor.authorD'Azevedo, Pedro Alvespt_BR
dc.contributor.authorFrazzon, Jeversonpt_BR
dc.contributor.authorFrazzon, Ana Paula Guedespt_BR
dc.date.accessioned2016-08-05T02:14:58Zpt_BR
dc.date.issued2015pt_BR
dc.identifier.issn0037-8682pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/144242pt_BR
dc.description.abstractIntroduction: Exposure to subinhibitory concentrations (SICs) of antimicrobials may alter the bacterial transcriptome. Methods: Here, we evaluated the expression of nine virulence-related genes in vancomycin-resistant enterococci (VRE) urinary tract infection isolates grown at SICs of vancomycin. Results: A Subinhibitory concentrations of vancomycin interferes with gene modulation, but does not affect the phenotype of a VRE strain in vitro. Conclusions: Subinhibitory concentrations of vancomycin may regulate the expression of virulence factors in vivo or contribute to the selection of vancomycin-resistant strains.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofRevista da Sociedade Brasileira de Medicina Tropical. Vol. 48, n. 5 (set./out. 2015), p. 617-621pt_BR
dc.rightsOpen Accessen
dc.subjectVREen
dc.subjectResistência à vancomicinapt_BR
dc.subjectBiofi imen
dc.subjectEnterococcus faecalispt_BR
dc.subjectExpressionen
dc.subjectFatores de virulênciapt_BR
dc.subjectBiofilmept_BR
dc.titleInfluence of a subinhibitory concentration of vancomycin on the in vitro expression of virulence-related genes in the vancomycin-resistant enterococcus faecalispt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000981187pt_BR
dc.type.originNacionalpt_BR


Thumbnail
Nome:
000981187.pdf
Tamanho:
745.2Kb
Formato:
PDF
Descrição:
Texto completo (inglês)
Visualizar/abrir
   

Este item está licenciado na Creative Commons License

Mostrar registro simples