Repositório Digital

A- A A+

Mechanical ventilation in patients in the intensive care unit of a general university hospital in southern Brazil : an epidemiological study an epidemiological study

.

Mechanical ventilation in patients in the intensive care unit of a general university hospital in southern Brazil : an epidemiological study an epidemiological study

Mostrar registro completo

Estatísticas

Título Mechanical ventilation in patients in the intensive care unit of a general university hospital in southern Brazil : an epidemiological study an epidemiological study
Autor Fialkow, Léa
Farenzena, Mauricio
Wawrzeniak, Iuri Christmann
Brauner, Janete Salles
Vieira, Silvia Regina Rios
Vigo, Álvaro
Bozzetti, Mary Clarisse
Abstract OBJECTIVES: To determine the characteristics, the frequency and the mortality rates of patients needing mechanical ventilation and to identify the risk factors associated with mortality in the intensive care unit (ICU) of a general university hospital in southern Brazil. METHOD: Prospective cohort study in patients admitted to the ICU who needed mechanical ventilation for at least 24 hours between March 2004 and April 2007. RESULTS: A total of 1,115 patients admitted to the ICU needed mechanical ventilation. The mortality rate was 51%. The mean age (± standard deviation) was 57±18 years, and the mean Acute Physiology and Chronic Health Evaluation II (APACHE II) score was 22.6±8.3. The variables independently associated with mortality were (i) conditions present at the beginning of mechanical ventilation, age (hazard ratio: 1.01; po0.001); the APACHE II score (hazard ratio: 1.01; po0.005); acute lung injury/acute respiratory distress syndrome (hazard ratio: 1.38; p=0.009), sepsis (hazard ratio: 1.33; p=0.003), chronic obstructive pulmonary disease (hazard ratio: 0.58; p=0.042), and pneumonia (hazard ratio: 0.78; p=0.013) as causes of mechanical ventilation; and renal (hazard ratio: 1.29; p=0.011) and neurological (hazard ratio: 1.25; p=0.024) failure, and (ii) conditions occurring during the course of mechanical ventilation, acute lung injuri/acute respiratory distress syndrome (hazard ratio: 1.31; po0.010); sepsis (hazard ratio: 1.53; po0.001); and renal (hazard ratio: 1.75; po0.001), cardiovascular (hazard ratio: 1.32; pp0.009), and hepatic (hazard ratio: 1.67; pp0.001) failure CONCLUSIONS: This large cohort study provides a comprehensive profile of mechanical ventilation patients in South America. The mortality rate of patients who required mechanical ventilation was higher, which may have been related to the severity of illness of the patients admitted to our ICU. Risk factors for hospital mortality included conditions present at the start of mechanical ventilation conditions that occurred during mechanical support.
Contido em Clinics. São Paulo. Vol. 71, n. 3 (mar. 2016), p. 145-151
Assunto Epidemiologia
Insuficiência respiratória aguda
Respiração artificial
[en] Acute respiratory failure
[en] Epidemiology
[en] Mechanical ventilation
[en] Mortality
[en] Risk factors
Origem Nacional
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/147204
Arquivos Descrição Formato
000990935.pdf (416.5Kb) Texto completo (inglês) Adobe PDF Visualizar/abrir

Este item está licenciado na Creative Commons License

Este item aparece na(s) seguinte(s) coleção(ões)


Mostrar registro completo

Percorrer



  • O autor é titular dos direitos autorais dos documentos disponíveis neste repositório e é vedada, nos termos da lei, a comercialização de qualquer espécie sem sua autorização prévia.
    Projeto gráfico elaborado pelo Caixola - Clube de Criação Fabico/UFRGS Powered by DSpace software, Version 1.8.1.