Repositório Digital

A- A A+

Transarterial embolization and percutaneous ethanol injection as an effective bridge therapy before liver transplantation for hepatitis C : related hepatocellular carcinoma

.

Transarterial embolization and percutaneous ethanol injection as an effective bridge therapy before liver transplantation for hepatitis C : related hepatocellular carcinoma

Mostrar registro completo

Estatísticas

Título Transarterial embolization and percutaneous ethanol injection as an effective bridge therapy before liver transplantation for hepatitis C : related hepatocellular carcinoma
Autor Chedid, Márcio Fernandes
Scaffaro, Leandro Armani
Chedid, Aljamir Duarte
Maciel, Antonio Carlos
Cerski, Carlos Thadeu Schmidt
Reis, Matheus Jara
Grezzana Filho, Tomáz de Jesus Maria
Araujo, Alexandre de
Leipnitz, Ian
Kruel, Cleber Dario Pinto
Álvares-da-Silva, Mário Reis
Kruel, Cleber Rosito Pinto
Abstract Background. Transarterial chemoembolization alone or in association with radiofrequency ablation is an effective bridging strategy for patients with hepatocellular carcinoma awaiting for a liver transplant.However, cost of this therapymay limit its utilization. This study was designed to evaluate the outcomes of a protocol involving transarterial embolization, percutaneous ethanol injection, or both methods for bridging hepatocellular carcinomas prior to liver transplantation. Methods. Retrospective review of all consecutive adult patients who underwent a first liver transplant as a treatment to hepatitis C-related hepatocellular carcinoma at our institution between 2002 and 2012. Primary endpoint was patient survival. Secondary endpoint was complete tumor necrosis. Results. Forty patients were analyzed, age 58 ± 7 years.There were 23 males (57.5%). Thirty-six (90%) out of the total 40 patients were within Milan criteria. Complete necrosis was achieved in 19 patients (47.5%). One-, 3-, and 5-year patient survival were, respectively, 87.5%, 75%, and 69.4%.Univariate analysis did not reveal any variable to impact on overall patient survival. Conclusions. Transarterial embolization, ethanol injection, or the association of both methods followed by liver transplantation comprises effective treatment strategy for hepatitis C-related hepatocellular carcinoma. This strategy should be adoptedwhenever transarterial chemoembolization and/or radiofrequency ablation are not available options.
Contido em Gastroenterology Research and Practice. Cairo. Vol. 2016 (2016), ID 9420274, 5 p.
Assunto Carcinoma hepatocelular
Hepatite C
Transplante de fígado
Origem Estrangeiro
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/159330
Arquivos Descrição Formato
001014620.pdf (1.276Mb) Texto completo (inglês) Adobe PDF Visualizar/abrir

Este item está licenciado na Creative Commons License

Este item aparece na(s) seguinte(s) coleção(ões)


Mostrar registro completo

Percorrer



  • O autor é titular dos direitos autorais dos documentos disponíveis neste repositório e é vedada, nos termos da lei, a comercialização de qualquer espécie sem sua autorização prévia.
    Projeto gráfico elaborado pelo Caixola - Clube de Criação Fabico/UFRGS Powered by DSpace software, Version 1.8.1.