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Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions

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Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions

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Título Accuracy of clinical diagnosis for the identification of potentially malignant disorders and malignant lip lesions
Autor Curra, Marina
Silva, Gabriela Salvadori da
Junges, Roger
Sant'Ana Filho, Manoel
Hugo, Fernando Neves
Martins, Manoela Domingues
Abstract The aim of this study was to assess the accuracy of clinical diagnosis for lip lesions based on sensitivity and specificity. The retrospective analysis focused on the detection of lesions caused by potentially malignant disorders (PMDs) and malignant lesions (n = 1195). All cases were classified as benign, PMD, and malignant lesions. Concordance between diagnoses based on clinical examination and those based on histopathological analysis was assessed, and accuracy for the identification of PMD and malignant lesions was calculated. Histopathological analysis revealed 44 lesion types; PMD and malignant lesions comprised 8.3% of all cases. Compared with histopathological analysis, clinical examination showed 97.4% accuracy for the identification of non-malignant and potentially malignant/malignant cases. Degrees of specific sensitivity ranged from 34% to 77% for different lesions, and were highest for autoimmune (77%) and reactive (72%) lesions. Positive and negative predictive values for the identification of PMD and malignant lesions were 81.9% and 98.9%, respectively. Clinical examination showed a high degree of accuracy for the detection of PMD and malignant lip lesions, indicating good reliability.
Contido em Brazilian oral research. São Paulo. Vol. 30, no. 1 (2016), p. e135, 1-8
Assunto Labio
Neoplasias bucais
Patologia bucal
[en] Clinical diagnosis
[en] Lip disease
[en] Neoplasm
Origem Nacional
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/164346
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