Repositório Digital

A- A A+

Is the emergence of fungal resistance to medical triazoles related to their use in the agroecosystems? : a mini review

.

Is the emergence of fungal resistance to medical triazoles related to their use in the agroecosystems? : a mini review

Mostrar registro completo

Estatísticas

Título Is the emergence of fungal resistance to medical triazoles related to their use in the agroecosystems? : a mini review
Autor Ribas, Aícha Daniela Ribas e
Spolti, Piérri
Del Ponte, Emerson Medeiros
Donato, Katarzyna Joanna Zawada
Schrekker, Henri Stephan
Fuentefria, Alexandre Meneghello
Abstract Triazole fungicides are used broadly for the control of infectious diseases of both humans and plants. The surge in resistance to triazoles among pathogenic populations is an emergent issue both in agriculture and medicine. The non-rational use of fungicides with site-specific modes of action, such as the triazoles, may increase the risk of antifungal resistance development. In the medical field, the surge of resistant fungal isolates has been related to the intensive and recurrent therapeutic use of a limited number of triazoles for the treatment and prophylaxis of many mycoses. Similarities in the mode of action of triazole fungicides used in these two fields may lead to cross-resistance, thus expanding the spectrum of resistance to multiple fungicides and contributing to the perpetuation of resistant strains in the environment. The emergence of fungicide-resistant isolates of human pathogens has been related to the exposure to fungicides used in agroecosystems. Examples include species of cosmopolitan occurrence, such as Fusarium and Aspergillus, which cause diseases in both plants and humans. This review summarizes the information about the most important triazole fungicides that are largely used in human clinical therapy and agriculture. We aim to discuss the issues related to fungicide resistance and the recommended strategies for preventing the emergence of triazole-resistant fungal populations capable of spreading across environments.
Contido em Brazilian journal of microbiology. Vol. 47, n. 4 (out./dez. 2016), p. 793-799
Assunto Farmácia
Fungicidas
[en] agriculture
[en] Cross-resistance
[en] Emerging fungaç áthogens
[en] Fungicide sensitivity
[en] medicine
Origem Nacional
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/164587
Arquivos Descrição Formato
001016286.pdf (1.384Mb) Texto completo (inglês) Adobe PDF Visualizar/abrir

Este item está licenciado na Creative Commons License

Este item aparece na(s) seguinte(s) coleção(ões)


Mostrar registro completo

Percorrer



  • O autor é titular dos direitos autorais dos documentos disponíveis neste repositório e é vedada, nos termos da lei, a comercialização de qualquer espécie sem sua autorização prévia.
    Projeto gráfico elaborado pelo Caixola - Clube de Criação Fabico/UFRGS Powered by DSpace software, Version 1.8.1.