Fluorescent test accurately predicts leak of ischemic colon anastomosis in rats
dc.contributor.author | Moschetti, Laura | pt_BR |
dc.contributor.author | Ghezzi, Tiago Leal | pt_BR |
dc.contributor.author | Müller, Belisa Gomes | pt_BR |
dc.contributor.author | Dias, Adriano Basso | pt_BR |
dc.contributor.author | Corleta, Oly Campos | pt_BR |
dc.date.accessioned | 2017-09-06T02:38:18Z | pt_BR |
dc.date.issued | 2017 | pt_BR |
dc.identifier.issn | 0102-8650 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/166189 | pt_BR |
dc.description.abstract | Purpose: To investigate if fluorescein fluorescent test can predict dehiscence in a model of ischemic colonic anastomosis in rats. Methods: This experimental controlled trial randomly assigned 55 rats to four groups. Anastomoses were performed in non-ischemic colon segments (control group) and in ischemic colon segments measuring 1, 2 or 3 cm long (groups 1, 2 and 3, respectively). Fluorescein was injected and the tissues were examined under ultraviolet light. Seven days later, a second-look surgery was performed to check for the presence or absence of anastomosis dehiscence. Results: Twenty-four rats presented anastomotic dehiscence during the second-look surgery. Reticular and nonfluorescent patterns were significantly associated with the occurrence of anastomotic dehiscence. Fluorescein fluorescence had a sensitivity of 95.8%, specificity of 89.2%, positive predictive value of 88.4%, negative predictive value of 96.2%, and accuracy of 92.3% to predict anastomotic dehiscence. Conclusion: Fluorescein fluorescent test can accurately predict leak in a model of ischemic colonic anastomosis in rats. | en |
dc.format.mimetype | application/pdf | pt_BR |
dc.language.iso | eng | pt_BR |
dc.relation.ispartof | Acta cirúrgica brasileira. São Paulo. Vol. 32, n. 6 (jun. 2017), p. 440-448 | pt_BR |
dc.rights | Open Access | en |
dc.subject | Anastomose cirúrgica | pt_BR |
dc.subject | Anastomosis | en |
dc.subject | Surgical | en |
dc.subject | Fluorescência | pt_BR |
dc.subject | Anastomotic Leak | en |
dc.subject | Fístula anastomótica | pt_BR |
dc.subject | Fluorescence | en |
dc.subject | Ratos | pt_BR |
dc.subject | Blood Supply | en |
dc.subject | Rats | en |
dc.title | Fluorescent test accurately predicts leak of ischemic colon anastomosis in rats | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 001046130 | pt_BR |
dc.type.origin | Nacional | pt_BR |
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