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The role of tympanic membrane retractions in cholesteatoma pathogenesis

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The role of tympanic membrane retractions in cholesteatoma pathogenesis

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Título The role of tympanic membrane retractions in cholesteatoma pathogenesis
Autor Rosito, Leticia Petersen Schmidt
Sperling, Neil
Teixeira, Adriane Ribeiro
Selaimen, Fábio André
Costa, Sady Selaimen da
Abstract Objective. To analyze the contralateral ear (CLE) of patients with cholesteatoma and to correlate the cholesteatoma growth pattern in the affected ear with the findings in the CLE. Methods. Videotoscopy of both ears in 432 patients with cholesteatomas classified as posterior epitympanic (PEC), posterior mesotympanic (PMC), two routes, or undetermined. Tympanic membrane (TM) retractions were classified by location and severity and TM perforations according to signs of previous TM retraction. Results. TM retraction was the most prevalent alteration in the CLE (42.6%). Cholesteatoma was observed in 17.4%. In patients with PEC, the retraction in the CLE was more frequent in the PF (66.7%) than in the PT (1.4%), and in those with two-route cholesteatoma, the retraction in the CLE most frequently involved both the PT and PF (65.6%; 𝑝 < 0.0001). Conclusion. Our results confirm the essential role of TM retraction at least in the earlier phases of cholesteatoma pathogenesis.
Contido em Biomed Research International. New York. Vol. 2018 (2018), ID 9817123, 5 p.
Assunto Colesteatoma
Membrana timpânica
Origem Estrangeiro
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/173915
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