• Diazepam and fluoxetine decrease the stress response in zebrafish 

      Abreu, Murilo Sander de; Koakoski, Gessi; Ferreira, Daiane; Oliveira, Thiago Acosta; Rosa, João Gabriel Santos; Gusso, Darlan; Giacomini, Ana Cristina Vendrametto Varrone; Piato, Angelo Luis Stapassoli; Barcellos, Leonardo Jose Gil (2014) [Artigo de periódico]
      The presence of pharmaceutical products in the aquatic environment has been reported in several studies. However, the impact of these drugs on living organisms is still uncharacterized. Here, we investigated the effects ...
    • Divergent action of fluoxetine in zebrafish according to responsivity to novelty 

      Fior, Débora; Dametto, Fernanda da Silveira; Fagundes, Michele; Rosa, João Gabriel Santos; Abreu, Murilo Sander de; Koakoski, Gessi; Idalencio, Renan; Barcellos, Heloisa Helena de Alcantara; Piato, Angelo Luis Stapassoli; Barcellos, Leonardo Jose Gil (2018) [Artigo de periódico]
      Here we show that the novel object recognition test can discriminate between high (HRN, neophobic) and low (LRN, neophilic) novelty responders in zebrafish populations. Especially when we observe the latency to the first ...
    • Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish 

      Abreu, Murilo Sander de; Giacomini, Ana Cristina Vendrametto Varrone; Koakoski, Gessi; Piato, Angelo Luis Stapassoli; Barcellos, Leonardo Jose Gil (2017) [Artigo de periódico]
      Fluoxetine is a selective serotonin reuptake inhibitor that increases serotonin concentration in the central nervous system and modulates various systems, including the control of sympathetic outflow and the hypothalamus ...
    • Environmental and pharmacological manipulations blunt the stress response of zebrafish in a similar manner 

      Giacomini, Ana Cristina Vendrametto Varrone; Abreu, Murilo Sander de; Zanandrea, Rodrigo; Saibt, Nathália; Friedrich, Maria Tereza; Koakoski, Gessi; Gusso, Darlan; Piato, Angelo Luis Stapassoli; Barcellos, Leonardo Jose Gil (2016) [Artigo de periódico]
      Here we provide evidence that both pharmacological and environmental manipulations similarly blunt the cortisol release in response to an acute stressor in adult zebrafish. Different groups of fish were maintained isolated ...
    • Waterborne aripiprazole blunts the stress response in zebrafish 

      Barcellos, Heloisa Helena de Alcantara; Kalichak, Fabiana; Rosa, João Gabriel Santos; Oliveira, Thiago Acosta; Koakoski, Gessi; Idalencio, Renan; Abreu, Murilo Sander de; Giacomini, Ana Cristina Vendrametto Varrone; Fagundes, Michele; Variani, Cristiane; Rossini, Mainara; Piato, Angelo Luis Stapassoli; Barcellos, Leonardo Jose Gil (2016) [Artigo de periódico]
      Here we provide, at least to our knowledge, the first evidence that aripiprazole (APPZ) in the water blunts the stress response of exposed fish in a concentration ten times lower than the concentration detected in the ...
    • Waterborne risperidone decreases stress response in zebrafish 

      Idalencio, Renan; Kalichak, Fabiana; Rosa, João Gabriel Santos; Oliveira, Tiago Acosta de; Koakoski, Gessi; Gusso, Darlan; Abreu, Murilo Sander de; Giacomini, Ana Cristina Vendrametto Varrone; Barcellos, Heloisa Helena de Alcantara; Piato, Angelo Luis Stapassoli; Barcellos, Leonardo Jose Gil (2015) [Artigo de periódico]
      The presence of drugs and their metabolites in surface waters and municipal effluents has been reported in several studies, but its impacts on aquatic organisms are not yet well understood. This study investigated the ...