Navegação Ciências Biológicas por Assunto "Macrófagos"
Resultados 1-8 de 8
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Attenuated inflammatory response of monocyte-derived macrophage from patients with BD : a preliminary report
(2019) [Artigo de periódico]Background: Innate immune system dysfunction has been recognized as an important element in the pathophysiology of bipolar disorder (BD). We aimed to investigate whether there are differences in the response of macrophages ... -
Effects of living and metabolically inactive mesenchymal stromal cells and their derivatives on monocytes and macrophages
(2021) [Artigo de periódico]Mesenchymal stromal cells (MSCs) are multipotent and self-renewing stem cells that have great potential as cell therapy for autoimmune and inflammatory disorders, as well as for other clinical conditions, due to their ... -
Elevated holo-transcobalamin in Gaucher disease type II : a case report
(2021) [Artigo de periódico]Gaucher disease (GD), one of the most common lysosomal disorders, is caused by deficiency of β-glucocerebrosidase. Based on the presence and severity of neurological complications, GD is classified into types I, II (the ... -
Extracellular mycobacterial DnaK polarizes macrophages to the M2-like phenotype
(2014) [Artigo de periódico]Macrophages are myeloid cells that play an essential role in inflammation and host defense, regulating immune responses and maintaining tissue homeostasis. Depending on the microenvironment, macrophages can polarize to two ... -
Integrated transcriptomics establish macrophage polarization signatures and have potential applications for clinical health and disease
(2015) [Artigo de periódico]Growing evidence defines macrophages (Mϕ) as plastic cells with wide-ranging states of activation and expression of different markers that are time and location dependent. Distinct from the simple M1/M2 dichotomy initially ... -
Metabolic fate of glutamine in lymphocytes, macrophages and neutrophils
(1999) [Artigo de periódico]Eric Newsholme’s laboratory was the first to show glutamine utilization by lymphocytes and macrophages. Recently, we have found that neutrophils also utilize glutamine. This amino acid has been shown to play a role in ... -
Phenolic compounds of red wine aglianico del vulture modulate the functional activity of macrophages via inhibition of NF-κB and the citrate pathway
(2021) [Artigo de periódico]Phenolic compounds of red wine powder (RWP) extracted from the Italian red wine Aglianico del Vulture have been investigated for the potential immunomodulatory and anti-inflammatory capacity on human macrophages. These ... -
Transcriptomic analysis reveals that mTOR pathway can be modulated in macrophage cells by the presence of cryptococcal cells
(2021) [Artigo de periódico]Cryptococcus neoformans and Cryptococcus gattii are the etiological agents of cryptococcosis, a high mortality disease. The development of such disease depends on the interaction of fungal cells with macrophages, in which ...