Navegação Ciências da Saúde por Autor "Macedo, Alexandre José"

Resultados 21-31 de 31

    • Pharmacological properties of specioside from the stem bark of Tabebuia aurea 

      Nocchi, Samara Requena; Kato, Natália Naomi; Almeida, Júlio Menta de; Ferreira, Alda Maria Teixeira; Kadri, Mônica Cristina Toffoli; Meirelles, Lyvia Eloiza de Freitas; Damke, Gabrielle Marconi Zago Ferreira; Consolaro, Márcia Edilaine Lopes; Rigo, Graziela de Vargas; Macedo, Alexandre José; Tasca, Tiana; Reis, Sharon Vieira dos; Alves, Flávio Macedo; Carollo, Carlos Alexandre; Silva, Denise Brentan (2020) [Artigo de periódico]
      Iridoids are secondary metabolites with several biological activities. They are often found in species of the genus Tabebuia Gomes ex A.P. de Candolle. Tabebuia aurea (Silva Manso) Benth. & Hook. F. ex S. Moore, Bignoniaceae, ...

    • Potential of medicinal plants from the Brazilian semi-arid region (Caatinga) against Staphylococcus epidermidis planktonic and biofilm lifestyles 

      Trentin, Danielle da Silva; Giordani, Raquel Brandt; Zimmer, Karine Rigon; Silva, Alexandre Gomes da; Silva, Márcia Vanusa da; Correia, Maria Tereza dos Santos; Baumvol, Israel Jacob Rabin; Macedo, Alexandre José (2011) [Artigo de periódico]
      Ethnopharmacological relevance: Medicinal plants from the Caatinga, a Brazilian xeric shrubland, are used in folk medicine to treat infections. These ethnopharmacological data can contribute to obtaining new antimicrobia ...

    • Promising antibiofilm activity of peptidomimetics 

      Von Borowski, Rafael Gomes; Gnoatto, Simone Cristina Baggio; Macedo, Alexandre José; Gillet, Reynald (2018) [Artigo de periódico]
      Pathogenic biofilms are a global health care concern, as they can cause extensive antibiotic resistance, morbidity, mortality, and thereby substantial economic loss. Scientific efforts have been made over the past few ...

    • Pseudonajide peptide derived from snake venom alters cell envelope integrity interfering on biofilm formation in Staphylococcus epidermidis 

      Schneider, Rafael de Oliveira; Barros, Muriel Primon de; Von Borowski, Rafael Gomes; Chat, Sophie; Nonin-Lecomte, Sylvie; Gillet, Reynald; Macedo, Alexandre José (2020) [Artigo de periódico]
      Background: The increase in bacterial resistance phenotype cases is a global health problem. New strategies must be explored by the scientific community in order to create new treatment alternatives. Animal venoms are a ...

    • Red pepper peptide coatings control Staphylococcus epidermidis adhesion and biofilm formation 

      Von Borowski, Rafael Gomes; Barros, Muriel Primon de; Silva, Denise Brentan; Lopes, Norberto Peporine; Zimmer, Karine Rigon; Staats, Charley Christian; Oliveira, Cristiane Bernardes de; Giudice, Emmanuel; Gillet, Reynald; Macedo, Alexandre José; Gnoatto, Simone Cristina Baggio; Zimmer, Aline Rigon (2020) [Artigo de periódico]
      Medical devices (indwelling) have greatly improved healthcare. Nevertheless, infections related to the use of these apparatuses continue to be a major clinical concern. Biofilms form on surfaces after bacterial adhesion, ...

    • Remarkable anti-trichomonas vaginalis activity of plants traditionally used by the MbYá-guarani indigenous group in Brazil 

      Brandelli, Clara Lia Costa; Vieira, Patrícia de Brum; Macedo, Alexandre José; Tasca, Tiana (2013) [Artigo de periódico]
      Trichomonas vaginalis, a flagellate protozoan, is the causative agent of trichomonosis, the most common nonviral sexually transmitted disease worldwide. Taking into account the increased prevalence of metronidazole-resistant ...

    • Resistência bacteriana no meio ambiente e implicações na clínica hospitalar 

      Caumo, Karin Silva; Duarte, Mariana; Cargnin, Simone Tasca; Ribeiro, Vanessa Bley; Tasca, Tiana; Macedo, Alexandre José (2010) [Artigo de periódico]
      O aumento da incidência de infecções microbianas resistentes a antibióticos adquiridas tanto na comunidade quanto nos hospitais tem chamado a atenção da comunidade de saúde. Neste contexto, muitos estudos têm demonstrado ...

    • Tannins possessing bacteriostatic effect impair pseudomonas aeruginosa adhesion and biofilm formation 

      Trentin, Danielle da Silva; Silva, Denise Brentan; Amaral, Matheus Weiler do; Zimmer, Karine Rigon; Silva, Márcia Vanusa da; Lopes, Norberto Peporine; Giordani, Raquel Brandt; Macedo, Alexandre José (2013) [Artigo de periódico]
      Plants produce many compounds that are biologically active, either as part of their normal program of growth and development or in response to pathogen attack or stress. Traditionally, Anadenanthera colubrina, Commiphora ...

    • Trans-translation is an appealing target for the development of new antimicrobial compounds 

      Silva, Rodrigo Campos da; D'Urso, Gaetano; Delalande, Olivier; Giudice, Emmanuel; Macedo, Alexandre José; Gillet, Reynald (2022) [Artigo de periódico]
      Because of the ever-increasing multidrug resistance in microorganisms, it is crucial that we find and develop new antibiotics, especially molecules with different targets and mechanisms of action than those of the antibiotics ...

    • Trichomonicidal and parasite membrane damaging activity of bidesmosic saponins from Manilkara rufula 

      Vieira, Patrícia de Brum; Silva, Nícolas Luiz Feijó; Menezes, Camila Braz; Silva, Márcia Vanusa da; Silva, Denise Brentan; Lopes, Norberto Peporine; Macedo, Alexandre José; Bastida, Jaume; Tasca, Tiana (2017) [Artigo de periódico]
      The infection caused by Trichomonas vaginalis is the most common but overlooked nonviral sexually transmitted disease worldwide. Treatment relies on one class of drugs, the 5- nitroimidazoles, but resistance is widespread. ...

    • Triterpene derivatives as relevant scaffold for new antibiofilm drugs 

      Silva, Gloria Narjara Santos da; Barros, Muriel Primon de; Macedo, Alexandre José; Gnoatto, Simone Cristina Baggio (2019) [Artigo de periódico]
      New medicines for the treatment of bacterial biofilm formation are required. For this reason, this study shows the in vitro activity of betulinic acid (BA), ursolic acid (UA) and their twenty derivatives against planktonic ...