Repositório Digital

A- A A+

Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia

.

Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia

Mostrar registro completo

Estatísticas

Título Comportamento dos marcadores inflamatórios e de injúria miocárdica na cirurgia cardíaca : correlação laboratorial com quadro clínico de síndrome pós-pericardiotomia
Outro título Behavior of inflammatory markers of myocardial injury in cardiac surgery : laboratory correlation with the clinical picture of potpericardiotomy syndrome
Autor Kohler, Ilmar
Saraiva, Paulo Jaconi
Wender, Orlando Carlos Belmonte
Zago, Alcides José
Abstract Objective- To verify the association of serum markers of myocardial injury, such as troponin I, creatinine kinase, and creatinine kinase isoenzyme MB, and inflammatory markers, such as tumor necrosis factor alpha (TNF-alpha), C-reactive protein, and the erythrocyte sedimentation rate in the perioperative period of cardiac surgery, with the occurrence of possible postpericardiotomy syndrome. Methods- This was a cohort study with 96 patients undergoing cardiac surgery assessed at the following 4 different time periods: the day before surgery (D0); the 3rd postoperative day (D3); between the 7th and 10th postoperative days (D7-10); and the 30th postoperative day (D30). During each period, we evaluated demo- graphic variables (sex and age), surgical variables (type and duration , extracorporeal circulation), and serum dosages of the markers of myocardial injury and inflam- matory response. Results - Of all patients, 12 (12.5%) met the clinical criteria for a diagnosis of postpericardiotomy syndrome, and their mean age was 10.3 years lower than the age of the others (P=0.02). The results of the serum markers for tissue injury and inflammatory response were not signifi- cantly different between the 2 assessed groups. No signifi- cant difference existed regarding either surgery duration or extracorporeal circulation. Conclusio- The patients who met the clinical criteria for postpericardiotomy syndrome were significan- tly younger than the others were. Serum markers for tissue injury and inflammatory response were not different in the clinically affected group, and did not correlate with the different types and duration of surgery or with extracorpo- real circulation.
Contido em Arquivos brasileiros de cardiologia. São Paulo. Vol. 81, n. 3 (sept. 2003), p. 279-284
Assunto Biomarcadores
Complicações
Diagnóstico clínico
Estudo comparativo
Pericardiectomia
Técnicas de laboratório clínico
[en] Cardiac surgery
[en] Inflammatory markers
[en] Injury markers
[en] Postpericardiotomy syndrome
Origem Nacional
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/19684
Arquivos Descrição Formato
000380141.pdf (148.1Kb) Texto completo (inglês) Adobe PDF Visualizar/abrir

Este item está licenciado na Creative Commons License

Este item aparece na(s) seguinte(s) coleção(ões)


Mostrar registro completo

Percorrer



  • O autor é titular dos direitos autorais dos documentos disponíveis neste repositório e é vedada, nos termos da lei, a comercialização de qualquer espécie sem sua autorização prévia.
    Projeto gráfico elaborado pelo Caixola - Clube de Criação Fabico/UFRGS Powered by DSpace software, Version 1.8.1.