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dc.contributor.authorWendland, Eliana Marcia da Rospt_BR
dc.contributor.authorPinto, Maria Eugênia Bresolinpt_BR
dc.contributor.authorDuncan, Bruce Bartholowpt_BR
dc.contributor.authorBelizán, José M.pt_BR
dc.contributor.authorSchmidt, Maria Inêspt_BR
dc.date.accessioned2010-05-05T04:15:55Zpt_BR
dc.date.issued2008pt_BR
dc.identifier.issn1471-2393pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/21559pt_BR
dc.format.mimetypeapplication/zippt_BR
dc.format.mimetypeapplication/zippt_BR
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofBMC pregnancy and childbirth. London. Vol. 8, no. 53 (2008)pt_BR
dc.rightsOpen Accessen
dc.subjectTabagismopt_BR
dc.subjectBackground: Gestational diabetes is a prevalent disease associated with adverse outcomes of pregnancy. Smoking as been associated with glucose intolerance during pregnancy in some but not all studies. Therefore, we aimed to systematically review all epidemiological evidence to examine the association between cigarette smoking during pregnancy and risk of developing gestational diabetes mellitus. Methods: We conducted a systematic review of articles published up to 2007, using PubMed, Embase, LILACS e CINAHL to identify the articles. Because this review focuses on studies of smoking during pregnancy, we excluded studies evaluating smoking outside pregnancy. Two investigators independently abstracted information on participant's characteristics, assessment of exposure and outcome, and estimates for the association under study.en
dc.subjectDiabetes gestacionalpt_BR
dc.subjectWe evaluated the studies for publication bias and performed heterogeneity analyses. We also assessed the effect of each study individually through sensitivity analysis. Results: We found and critically reviewed 32 studies, of which 12 met the criteria for inclusion in the review. Most of the studies provided only unadjusted measurements. Combining the results of the individual studies, we obtained a crude odds ratio of 1.03 (99% CI 0.85–1.25). Only 4 studies presented adjusted measurements of association, and no association was found when these alone were analyzed (OR 0.95; 99% CI 0.85–1.07). Subgroup analysis could not be done due to small sample size. Conclusion: The number of studies is small, with major heterogeneity in research design and findings. Taken together, current data do not support an association between cigarette smoking during pregnancy and the risk of gestational diabetes.en
dc.subjectGravidezpt_BR
dc.subjectFatores de riscopt_BR
dc.subjectRevisão sistemáticapt_BR
dc.titleCigarette smoking and risk of gestational diabetes : a systematic review of observational studiespt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000717207pt_BR
dc.type.originEstrangeiropt_BR


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