Mostrar registro simples

dc.contributor.authorRodrigues, Ticiana da Costapt_BR
dc.contributor.authorBiavatti, Karinapt_BR
dc.contributor.authorAlmeida, Fernando Kude dept_BR
dc.contributor.authorGross, Jorge Luizpt_BR
dc.date.accessioned2011-08-04T06:01:02Zpt_BR
dc.date.issued2010pt_BR
dc.identifier.issn0100-879Xpt_BR
dc.identifier.urihttp://hdl.handle.net/10183/30514pt_BR
dc.description.abstractThe objective of the present study was to evaluate the risk factors associated with the presence of coronary artery calcification (CAC) in patients with type 1 diabetes (T1D). A cross-sectional study was conducted on 100 consecutive T1D patients without coronary artery disease, with at least 5 years of diabetes and absence of end-stage renal disease. Mean age was 38 ± 10 years and 57% were males. CAC score was measured by multidetector computed tomography (Siemens Sensation 64 Cardiac). The insulin resistance index was measured using the estimated glucose disposal rate (eGDR). The eGDR was lower among CAC-positive patients than among CAC-negative patients, suggesting an increased insulin resistance. In a logistic regression model adjusted for age (at 10-year intervals), eGDR, diabetic nephropathy and gender, CAC was associated with age [OR = 2.73 (95%CI = 1.53-4.86), P = 0.001] and with eGDR [OR = 0.08 (95%CI = 0.02-0.21), P = 0.004]. In T1D subjects, insulin resistance is one of the most important risk factors for subclinical atherosclerosis.en
dc.format.mimetypeapplication/pdf
dc.language.isoengpt_BR
dc.relation.ispartofBrazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas. Vol. 43, n. 11 (nov. 2010), p. 1084-1087pt_BR
dc.rightsOpen Accessen
dc.subjectDiabetes mellitus tipo 1pt_BR
dc.subjectType 1 diabetesen
dc.subjectCoronary artery calcificationen
dc.subjectCalcinosept_BR
dc.subjectCardiomiopatiaspt_BR
dc.subjectInsulin resistanceen
dc.subjectResistência à insulinapt_BR
dc.titleCoronary artery calcification is associated with insulin resistance index in patients with type 1 diabetespt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000771019pt_BR
dc.type.originNacionalpt_BR


Thumbnail
   

Este item está licenciado na Creative Commons License

Mostrar registro simples