• Chronic exposure to ethanol causes steatosis and inflammation in zebrafish liver 

      Schneider, Ana Cláudia Reis; Gregório, Cleandra; Cruz, Carolina Uribe; Guizzo, Ranieli; Malysz, Tais; Heuser, Maria Cristina Faccioni; Longo, Larisse; Silveira, Themis Reverbel da (2017) [Artigo de periódico]
      AIM To evaluate the effects of chronic exposure to ethanol in the liver and the expression of inflammatory genes in zebrafish. METHODS Zebrafish (n = 104), wild type, adult, male and female, were divided into two groups: ...
    • Enriched environment prevents oxidative stress in zebrafish submitted to unpredictable chronic stress 

      Marcon, Matheus Felipe; Mocelin, Ricieri Naue; Sachett, Adrieli; Siebel, Anna Maria; Herrmann, Ana Paula; Piato, Angelo Luis Stapassoli (2018) [Artigo de periódico]
      Background. The enriched environment (EE) is a laboratory housing model that emerged from efforts to minimize the impact of environmental conditions on laboratory animals. Recently, we showed that EE promoted positive ...
    • Experimental model of hepatic steatosis by fructose in adult zebrafish : a pilot study 

      Ferrari, Jéssica Tonin; Ayres, Raquel; Hammes, Thais Ortiz; Silveira, Themis Reverbel da; Cruz, Carolina Uribe (2018) [Artigo de periódico]
      The consumption of fructose has been questioned, since its increase has led to an associated increase in steatosis caused by nonalcoholic fatty liver disease. Despite the advantages presented by the zebrafish as an animal ...
    • Implementação de um novo modelo de experimentação animal : zebrafish 

      Schneider, Ana Cláudia Reis; Santos, Jorge Luiz dos; Porawski, Marilene; Schaefer, Pedro Guilherme; Maurer, Rafael Lucyk; Matte, Ursula da Silveira; Silveira, Themis Reverbel da (2009) [Artigo de periódico]
      O Danio rerio (zebrafish, paulistinha) é um pequeno peixe de água-doce, que vem sendo utilizado como modelo de animal para o estudo de numerosas doenças humanas. A sua facilidade de manutenção e reprodução e os métodos ...
    • N-acetylcysteine protects against motor, optomotor and morphological deficits induced by 6-OHDA in zebrafish larvae 

      Benvenutti, Radharani; Marcon, Matheus Felipe; Reis, Carlos Guilherme Rosa; Nery, Laura Roesler; Miguel, Camila; Herrmann, Ana Paula; Vianna, Monica Ryff Moreira Roca; Piato, Angelo Luis Stapassoli (2018) [Artigo de periódico]
      Background: Parkinson’s disease (PD) is the second most common neurodegenerative disorder. In addition to its highly debilitating motor symptoms, non-motor symptoms may precede their motor counterparts by many years, which ...