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dc.contributor.authorVerzeletti, Giliano Nicolinipt_BR
dc.contributor.authorGaio, Eduardo Josépt_BR
dc.contributor.authorLinhares, Daniele Sigalpt_BR
dc.contributor.authorRösing, Cassiano Kuchenbeckerpt_BR
dc.date.accessioned2012-11-21T01:50:44Zpt_BR
dc.date.issued2012pt_BR
dc.identifier.issn1678-7757pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/61179pt_BR
dc.description.abstractObesity has been linked to higher inflammatory status and periodontal breakdown. Objective: The purpose of this study was to investigate the effect of obesity on alveolar bone loss in experimental periodontitis in rats. Material and Methods: Twenty-four female Wistar rats were randomly divided into two groups: obese (n=13), which were fed with “cafeteria diet” (CAF diet - high amounts of sucrose and fat) for 90 days in order to gain weight, and non-obese (n=11) regularly fed rats. Ligature-induced experimental periodontitis was created in all animals. Body weight differed statistically between obese and non-obese groups (277.59 and 223.35 g, respectively) at the moment of the ligature placement. Morphometric registration of alveolar bone loss was carried out after 30 days of ligature placement to determine the effect of obesity on the progression of experimental peiodontitis. Results: Intra-group comparisons showed significantly higher alveolar bone loss mean values in maxillary teeth with ligature (P<0.05). Alveolar bone loss [mean (SD),mm] was not statistically different between obese and non-obese groups [0.71 (0.09) and 0.65 (0.07) mm, respectively]. However, when palatal sides are analyzed separately, obese group presented significantly higher alveolar bone loss P<0.05) as compared to non-obese [0.68 (0.12) and 0.53 (0.13) mm, respectively]. Conclusions: In spite of the weak differences, it is possible to conclude that the progression of alveolar bone loss in ligature-induced periodontitis can be potentially influenced by body weight in rats.en
dc.format.mimetypeapplication/pdf
dc.language.isoengpt_BR
dc.relation.ispartofJournal of applied oral science. Bauru. Vol. 20, no. 2 (Mar./Apr. 2012), p. 218-221pt_BR
dc.rightsOpen Accessen
dc.subjectDoenças periodontaispt_BR
dc.subjectBody weighten
dc.subjectInflammationen
dc.subjectObesidadept_BR
dc.subjectPerda óssea alveolarpt_BR
dc.subjectPeriodontal diseasesen
dc.titleEffect of obesity on alveolar bone loss in experimental periodontitis in Wistar ratspt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000852268pt_BR
dc.type.originNacionalpt_BR


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