Repositório Digital

A- A A+

Evaluation of cell proliferation rate in non-dysplastic leukoplakias

.

Evaluation of cell proliferation rate in non-dysplastic leukoplakias

Mostrar registro completo

Estatísticas

Título Evaluation of cell proliferation rate in non-dysplastic leukoplakias
Autor Hildebrand, Laura de Campos
Carrard, Vinícius Coelho
Lauxen, Isabel da Silva
Quadros, Onofre Francisco de
Chaves, Anna Cecília Moraes
Sant'Ana Filho, Manoel
Abstract Objective: Analyze whether the most frequent cases of non-dysplastic leukoplakias, hyperkeratosis (H), acanthosis (A), and hyperkeratosis with acanthosis (HA) have similar cell proliferation rates and to compare them with epithelial dysplastic (ED) leukoplakias and normal oral epithelium (NOE).Study design: The sample comprised 10 cases of normal oral epithelium, 10 cases of hyperkeratosis, 10 cases of acanthosis, 10 cases of hyperkeratosis with acanthosis and 10 cases of epithelial dysplasia. The mean number of AgNORs per nucleus (mAgNOR) and the mean percentage of cells with 1, 2, 3 and 4 or more AgNORs per nucleus (pAgNOR) were recorded. Results: The results of mAgNOR showed differences between disorders in the evaluation of the basal layer, of the parabasal layer, and in the overall evaluation. mAgNOR and pAgNOR=2 increased progressively from normal oral epithelium to hyperkeratosis with acanthosis, hyperkeratosis, acanthosis and epithelial dysplasia (p<0.05). Cell proliferation rate was different between different subtypes of non-dysplastic leukoplakias and this group presented a higher proliferative behavior when compared to normal oral epithelium. Conclusion: It may be suggested that non-dysplastic leukoplakias had different characteristics regarding cell proliferation rates and sometimes showed a proliferative behavior similar to that found in epithelial dysplasia. More studies should be conduced to increase knowledge about the biological profile of non-dysplastic leukoplakias, especially as it pertains to acanthosis.
Contido em Medicina oral, patología oral y cirugía bucal. Valencia. Vol. 15, no. 2 (Mar. 2010), p. e328-e334
Assunto Leucoplasia bucal
Mucosa bucal : Doencas
Patologia bucal
Proliferação celular
[en] Acanthosis
[en] AgNOR
[en] Cell proliferation
[en] Epithelial dysplasia
[en] Hyperkeratosis
[en] Leukoplakia
Origem Estrangeiro
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/61369
Arquivos Descrição Formato
000785187.pdf (415.6Kb) Texto completo (inglês) Adobe PDF Visualizar/abrir

Este item está licenciado na Creative Commons License

Este item aparece na(s) seguinte(s) coleção(ões)


Mostrar registro completo

Percorrer



  • O autor é titular dos direitos autorais dos documentos disponíveis neste repositório e é vedada, nos termos da lei, a comercialização de qualquer espécie sem sua autorização prévia.
    Projeto gráfico elaborado pelo Caixola - Clube de Criação Fabico/UFRGS Powered by DSpace software, Version 1.8.1.