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Título | Uniparental genetic markers in South Amerindians |
Autor |
Machado, Rafael Bisso
Bortolini, Maria Cátira Salzano, Francisco Mauro |
Abstract | A comprehensive review of uniparental systems in South Amerindians was undertaken. Variability in the Y-chromosome haplogroups were assessed in 68 populations and 1,814 individuals whereas that of Y-STR markers was assessed in 29 populations and 590 subjects. Variability in the mitochondrial DNA (mtDNA) haplogroup was examined in 108 populations and 6,697 persons, and sequencing studies used either the complete mtDNA genome or the highly variable segments 1 and 2. The diversity of the markers made it difficult to establish a general picture of Y-chromosome variability in the populations studied. However, haplogroup Q1a3a* was almost always the most prevalent whereas Q1a3* occurred equally in all regions, which suggested its prevalence among the early colonizers. The STR allele frequencies were used to derive a possible ancient Native American Q-clade chromosome haplotype and five of six STR loci showed significant geographic variation. Geographic and linguistic factors moderately influenced the mtDNA distributions (6% and 7%, respectively) and mtDNA haplogroups A and D correlated positively and negatively, respectively, with latitude. The data analyzed here provide rich material for understanding the biological history of South Amerindians |
Contido em | Genetics and molecular biology. Ribeirão Preto, SP. Vol. 35, n. 2 (jun. 2012), p. 365-387 |
Assunto |
Ameríndios
Brasil Cromossomo Y DNA mitocondrial [en] genetics [en] language and geography [en] mitochondrial DNA [en] Native Americans [en] South Amerindians [en] Y-chromosome |
Origem | Nacional |
Tipo | Artigo de periódico |
URI | http://hdl.handle.net/10183/87818 |
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