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dc.contributor.authorAraujo, Anelise Bergmannpt_BR
dc.contributor.authorBerne, Maria Elisabeth Airespt_BR
dc.date.accessioned2014-03-01T01:55:03Zpt_BR
dc.date.issued2013pt_BR
dc.identifier.issn1413-8670pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/88125pt_BR
dc.description.abstractResults of Chagas’ disease diagnosis show disagreement. The aim of this study was to compare commercial tests for Chagas’ disease serodiagnosis in southern Brazil. A total of 161 samples were evaluated. Three enzyme-linked immunosorbent assays, one indirect hemagglutination and one indirect immunofluorescence were assessed. Trypomastigote excreted-secreted antigen-blot was a confirmatory method. From 161 samples, 65.84% were positive in all tests, while 34.16% presents mismatch result in at least one of the tests. All techniques tested presented false-positive and/or false-negative results as follows: Enzyme-linked immunosorbent assay 1 had more false-positive results (lower specificity), indirect immunofluorescence had the highest rate of false-negative results (lower sensitivity), enzyme-linked immunosorbent assays had fewer false-negative results (higher sensitivity), while indirect hemagglutination showed no false-positive result (higher specificity). Knowing the characteristics of techniques make it possible to combine them and obtain more reliable diagnosis. Therefore, it seems useful to combine techniques for diagnosing this infection.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofThe Brazilian journal of infectious diseases. Salvador. Vol. 17, n. 2 (Mar./Apr. 2013), p. 174-178.pt_BR
dc.rightsOpen Accessen
dc.subjectTrypanosoma cruzien
dc.subjectTrypanosoma cruzipt_BR
dc.subjectDoença de Chagaspt_BR
dc.subjectChagas’ diseaseen
dc.subjectSerodiagnosis Immunoassaysen
dc.subjectTestes sorológicospt_BR
dc.subjectImunoensaiopt_BR
dc.titleConventional serological performance in diagnosis of Chagas’ disease in southern Brazilpt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000906181pt_BR
dc.type.originNacionalpt_BR


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