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The effects of diet- and diet plus exercise-induced weight loss on basal metabolic rate and acylated ghrelin in grade 1 obese subjects

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The effects of diet- and diet plus exercise-induced weight loss on basal metabolic rate and acylated ghrelin in grade 1 obese subjects

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Título The effects of diet- and diet plus exercise-induced weight loss on basal metabolic rate and acylated ghrelin in grade 1 obese subjects
Autor Lopes, André Luiz
Fayh, Ana Paula Trussardi
Campos, Luísa Garcia de Souza
Teixeira, Bruno Costa
Carteri, Randhall Bruce Kreismann
Ribeiro, Jerri Luiz
Friedman, Rogério
Oliveira, Álvaro Reischak de
Abstract Background: Diet and exercise are often prescribed as primary intervention regarding obesity-related disorders. Additionally, recent studies have shown beneficial effects of weight loss through diet and exercise in ghrelin concentrations in obese subjects. The aim of this study was to evaluate the effects of a 5% weight loss on lipid profile, resting metabolic rate (RMR), and acylated ghrelin (AG) using two different methods of intervention (diet or diet plus exercise). Materials and methods: Eighteen subjects (twelve women and six men) aged 20–40 years with a body mass index of 30–34.9 kg/m2 (grade 1 obesity) were randomized into two intervention groups: diet (n=9) or diet plus exercise (n=9). Both groups underwent treatment until 5% of the initial body weight was lost. At baseline and upon completion, RMR and AG were analyzed. Results: Both groups showed a significant decrease in body fat percentage and fat mass. The diet-plus-exercise group showed a decrease in AG (pre: 54.4±25.3 pg/mL and post: 33.2±19.1 pg/mL) and an increase in RMR (pre: 1,363±379 kcal/day, post: 1,633±223 kcal/day). Conclusion: These data suggest that diet plus exercise induced weight loss and had beneficial effects on AG concentration and RMR, essential factors to ensure the benefits of a weight-loss program.
Contido em Diabetes, metabolic syndrome and obesity : targets and therapy. Auckland, N.Z. Vol. 6 (Nov. 2013), p. 469-475
Assunto Dieta
Metabolismo energetico
Obesidade
Terapia por exercício
[en] Diet
[en] Energy regulation
[en] Exercise therapy
[en] Hormones
[en] Obesity
Origem Estrangeiro
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/89725
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