Influence of supragingival biofilm control and smoking habit on Interleukin-1β concentration
dc.contributor.author | Gomes, Sabrina Carvalho | pt_BR |
dc.contributor.author | Abascal, C.C. | pt_BR |
dc.contributor.author | Haas, Alex Nogueira | pt_BR |
dc.contributor.author | Angst, Patrícia Daniela Melchiors | pt_BR |
dc.contributor.author | Oppermann, Rui Vicente | pt_BR |
dc.contributor.author | Marcantonio, Rosemary Adriana Chierici | pt_BR |
dc.date.accessioned | 2016-08-11T02:15:51Z | pt_BR |
dc.date.issued | 2015 | pt_BR |
dc.identifier.issn | 1806-8324 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/10183/147077 | pt_BR |
dc.description.abstract | T his i nvestigation c ompared g ingival c revicular fl uid (GCF) interleukin-1β (IL-1β) concentrations in periodontitis patients subjected to a strict supragingival biofilm control (Supra) for 6 months. Never-smokers (23) and smokers (n = 20; 19.6 ± 11.8 cigarettes/day) moderate-to-severe chronic periodontitis patients underwent a 6 months period of supragingival control with weekly recall visits. Periodontal probing depth (PPD), bleeding on probing (BOP) and GCF samples (from different PPD category sites: 3-5 mm and 6–10 mm) were obtained at the baseline, 30, and 180 days. IL-1β was assessed by enzyme-linked immunosorbent assay. Generalized estimating equations were used to fit prediction models of IL-1β changes, considering the dependence between the examinations, and using only data from experimental sites. Overall IL-1β concentrations decreased from 3.2 pg/μL to 1.9 pg/μL. Higher baseline IL-1β concentrations were associated with higher baseline PPD values in both groups. There were no differences in IL-1β concentrations between never-smokers and smokers over time for any PPD category. Higher baseline PPD values and the presence of BOP on day 180 were significantly associated with higher IL-1β concentrations. A strict Supra regimen reduced IL-1β concentrations over time in periodontitis patients. The benefits observed for smokers underline the importance of oral hygiene measures, even considering the presence of this important risk factor. | en |
dc.format.mimetype | application/pdf | |
dc.language.iso | por | pt_BR |
dc.relation.ispartof | Brazilian oral research. São Paulo. Vol. 29, no. 1 (2015), p. 1-8 | pt_BR |
dc.rights | Open Access | en |
dc.subject | Dental plaque | en |
dc.subject | Biofilmes | pt_BR |
dc.subject | Hábito de fumar | pt_BR |
dc.subject | Interleukin-1Beta | en |
dc.subject | Periodontal disease | en |
dc.subject | Placa dentaria | pt_BR |
dc.subject | Doenças periodontais | pt_BR |
dc.subject | Smoking | en |
dc.title | Influence of supragingival biofilm control and smoking habit on Interleukin-1β concentration | pt_BR |
dc.type | Artigo de periódico | pt_BR |
dc.identifier.nrb | 000988183 | pt_BR |
dc.type.origin | Nacional | pt_BR |
Este item está licenciado na Creative Commons License
-
Artigos de Periódicos (39124)Ciências da Saúde (10550)