Browsing Health Sciences by Author "Tobo, Patricia R."
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Effect of dimethylsufoxide on sphingomyelinase activity and cholesterol metabolism in Niemann-Pick type C fibroblasts
Scalco, Fernanda Bertao; Giugliani, Roberto; Tobo, Patricia R.; Coelho, Janice Carneiro (1999) [Journal article]Niemann-Pick type C (NPC) fibroblasts present a large concentration of cholesterol in their cytoplasm due to a still unidentified deficiency in cholesterol metabolism. The influence of dimethylsulfoxide (DMSO) on the amount ...