• Antitumor activities and cellular changes induced by TrkB inhibition in medulloblastoma 

      Thomaz, Amanda Cristina Godot; Pinheiro, Kelly de Vargas; Souza, Bárbara Kunzler; Gregianin, Lauro José; Brunetto, Algemir Lunardi; Brunetto, Andre Tessainer; Farias, Caroline Brunetto de; Jaeger, Mariane da Cunha; Ramaswamy, Vijay; Nor, Carolina; Taylor, Michael David; Roesler, Rafael (2019) [Artigo de periódico]
      Neurotrophins are critically involved in regulating normal neural development and plasticity. Brain-derived neurotrophic factor (BDNF), a neurotrophin that acts by binding to the tropomyosin receptor kinase B (TrkB) receptor, ...
    • EHMT2/G9a as an epigenetic target in pediatric and adult brain tumors 

      Souza, Bárbara Kunzler; Freire, Natália Hogetop; Jaeger, Mariane da Cunha; Farias, Caroline Brunetto de; Brunetto, Algemir Lunardi; Brunetto, Andre Tessainer; Roesler, Rafael (2021) [Artigo de periódico]
      Epigenetic mechanisms, including post-translational modifications of DNA and histones that influence chromatin structure, regulate gene expression during normal development and are also involved in carcinogenesis and cancer ...