• Pharmacological properties of specioside from the stem bark of Tabebuia aurea 

      Nocchi, Samara Requena; Kato, Natália Naomi; Almeida, Júlio Menta de; Ferreira, Alda Maria Teixeira; Kadri, Mônica Cristina Toffoli; Meirelles, Lyvia Eloiza de Freitas; Damke, Gabrielle Marconi Zago Ferreira; Consolaro, Márcia Edilaine Lopes; Rigo, Graziela de Vargas; Macedo, Alexandre José; Tasca, Tiana; Reis, Sharon Vieira dos; Alves, Flávio Macedo; Carollo, Carlos Alexandre; Silva, Denise Brentan (2020) [Artigo de periódico]
      Iridoids are secondary metabolites with several biological activities. They are often found in species of the genus Tabebuia Gomes ex A.P. de Candolle. Tabebuia aurea (Silva Manso) Benth. & Hook. F. ex S. Moore, Bignoniaceae, ...
    • Pharmacological treatment and staging in bipolar disorder : evidence from clinical practice 

      Goi, Pedro Domingues; Bücker, Joana; Sulzbach, Miréia Fortes Vianna; Rosa, Adriane Ribeiro; Grande, Iria; Chendo, Inês; Sodré, Leonardo de Almeida; Kauer-Sant'Anna, Márcia; Silveira, Leonardo Evangelista da; Kunz, Maurício; Ceresér, Keila Maria Mendes; Gama, Clarissa Severino; Massuda, Raffael (2015) [Artigo de periódico]
      Objective: Staging models for medical diseases are widely used to guide treatment and prognosis. Bipolar disorder (BD) is a chronic condition and it is among the most disabling disorders in medicine. The staging model ...
    • Pharmacotherapy of bipolar disorder in children and adolescents : an update 

      Peruzzolo, Tatiana Lauxen; Tramontina, Silzá; Rohde, Luis Augusto Paim; Zeni, Cristian Patrick (2013) [Artigo de periódico]
      Objective: To review the options for acute and maintenance pharmacological treatment of bipolar disorder in children and adolescents, including the treatment of bipolar depression and comorbid attention deficit/hyperactivity ...
    • A phase 2, double-blind, placebo-controlled, randomized study of fresolimumab in patients with steroid-resistant primary focal segmental glomerulosclerosis 

      Vincenti, Flavio; Fervenza, Fernando Custodio; Campbell, Kirk Nicholas; Díaz, Montserrat M.; Gesualdo, Loreto; Nelson, Peter; Praga, Manuel; Radhakrishnan, Jai; Sellin, Lorenz K.; Singh, Ajay; Thornley-Brown, Denyse P.; Veronese, Francisco José Veríssimo; Accomando, Beverly; Engstrand, Sara; Ledbetter, Steven R.; Lin, Julie; Neylan, John F.; Tumlin, James A.; Focal Segmental Glomerulosclerosis Study Group (2017) [Artigo de periódico]
      Introduction: Steroid-resistant focal segmental glomerulosclerosis (SR-FSGS) is a common glomerulopathy associated with nephrotic range proteinuria. Treatment goals are reduction in proteinuria, which can delay end-stage ...
    • A phase II, randomized, double-blind, placebo controlled, dose-response trial of the melatonin effect on the pain threshold of healthy subjects 

      Stefani, Luciana Paula Cadore; Müller, Suzana; Torres, Iraci Lucena da Silva; Razzolini, Bruna Regis; Rozisky, Joanna Ripoll; Fregni, Felipe; Markus, Regina Pekelmann; Caumo, Wolnei (2013) [Artigo de periódico]
      Background: Previous studies have suggested that melatonin may produce antinociception through peripheral and central mechanisms. Based on the preliminary encouraging results of studies of the effects of melatonin on pain ...
    • pH effect on stability and kinetics degradation of nitazoxanide in solution 

      Barbosa, Fábio de Souza; Pezzi, Leonardo Capra; Sorrentino, Julia Medeiros; Steppe, Martin; Volpato, Nadia Maria; Mendez, Andreas Sebastian Loureiro (2020) [Artigo de periódico]
      Stability studies correspond to a set of tests designed to assess changes in the quality of a given drug over time and under the influence of a number of factors. Among these factors, pH plays an important role, due to the ...
    • Phenolic enriched extract of baccharis trimera presents anti-inflammatory and antioxidant activities 

      Oliveira, Cristiane Bernardes de; Comunello, Lucimara Nardi; Lunardelli, Adroaldo; Amaral, Robson Henrich; Pires, Melissa Guerra Simões; Silva, Gabriela Lucas da; Manfredini, Vanusa; Vargas, Carmen Regla; Gnoatto, Simone Cristina Baggio; Oliveira, Jarbas Rodrigues de; Gosmann, Grace (2012) [Artigo de periódico]
      Baccharis trimera is a plant popularly used as a tea and to treat gastrointestinal diseases and inflammatory processes as well. The total phenolic content was determined and the antioxidant and anti-inflammatory activities ...
    • Phenotype-oriented NGS panels for mucopolysaccharidoses : validation and potential use in the diagnostic flowchart 

      Fachin, Ana Carolina Brusius; Siebert, Marina; Leão, Delva Pereira; Málaga, Diana Elizabeth Rojas; Pasqualim, Gabriela; Trapp, Franciele Barbosa; Matte, Ursula da Silveira; Giugliani, Roberto; Leistner-Segal, Sandra (2019) [Artigo de periódico]
      Mucopolysaccharidosis (MPS) are a group of rare genetic disorders caused by deficiency in the activity of specific lysosomal enzymes required for the degradation of glycosaminoglycans (GAGs). A defect in the activity of ...
    • Phenotyping and genotyping methods applied to investigate the relatedness of brazilian isolates of enterobacter cloacae 

      Darini, A.L.C.; Magalhães, V.D.; Levy, C.L.; Barth, Afonso Luis; Coscina, A.L. (1999) [Artigo de periódico]
      In order to evaluate the resolving power of several typing methods to identify relatedness among Brazilian strains of Enterobacter cloacae, we selected twenty isolates from different patients on three wards of a University ...
    • Phenylketonuria and gut microbiota : a controlled study based on next-generation sequencing 

      Oliveira, Felipe Pinheiro de; Mendes, Roberta Hack; Dobbler, Priscila Caroline Thiago; Mai, Volker; Pylro, Victor Satler; Waugh, Sheldon G.; Vairo, Filippo Pinto e; Refosco, Lilia Farret; Roesch, Luiz Fernando Wurdig; Schwartz, Ida Vanessa Doederlein (2016) [Artigo de periódico]
      Phenylketonuria (PKU) is an inborn error of metabolism associated with high blood levels of phenylalanine (Phe). A Phe-restricted diet supplemented with L-amino acids is the main treatment strategy for this disease; if ...
    • PH e titrabilidade ácida de sucos artificiais de limão 

      Corso, Ana Carolina; Hugo, Fernando Neves; Padilha, Dalva Maria Pereira (2002) [Artigo de periódico]
    • Philadelphia-negative chronic myeloproliferative neoplasms 

      Bittencourt, Rosane Isabel; Vassallo, Jose; Chauffaille, Maria de Lourdes Lopes Ferrari; Xavier, Sandra Guerra; Pagnano, Katia Borgia Barbosa; Nascimento, Ana Clara Kneese Virgilio do; Souza, Cármino Antônio de; Chiattone, Carlos Sérgio (2012) [Artigo de periódico]
      Chronic myeloproliferative diseases without the Philadelphia chromosome marker (Ph-), although first described 60 years ago, only became the subject of interest after the turn of the millennium. In 2001, the World Health ...
    • Phonemic verbal fluency and severity of anxiety disorders in young children 

      Toazza, Rudineia; Salum Junior, Giovanni Abrahão; Sousa, Diogo Araújo de; Jarros, Rafaela Behs; Salles, Jerusa Fumagalli de; Manfro, Gisele Gus (2016) [Artigo de periódico]
      Introduction: Previous studies have implicated impaired verbal fluency as being associated with anxiety disorders in adolescents. Objectives: To replicate and extend previously reported evidence by investigating whether ...
    • Phonetic transcription of spontaneous children's speech with the aid of software : a systematic review 

      Caumo, Débora Tomazi Moreira; França, Marcio Pezzini; Silva, Clecio Homrich da (2022) [Artigo de periódico]
      O objetivo do estudo foi identificar, sintetizar e classificar os softwares atualmente disponíveis que podem auxiliar na tarefa de transcrição fonética da fala espontânea de pré-escolares, para avaliar o desenvolvimento ...
    • A phosphodiesterase 4-controlled switch between memory extinction and strengthening in the hippocampus 

      Roesler, Rafael; Reolon, Gustavo Kellermann; Maurmann, Natasha; Schwartsmann, Gilberto; Schroder, Nadja; Amaral, Olavo Bohrer; Valvassori, Samira da Silva; Quevedo, João Luciano de (2014) [Artigo de periódico]
      Established fear-related memories can undergo phenomena such as extinction or reconsolidation when recalled. Extinction probably involves the creation of a new, competing memory trace that decreases fear expression, whereas ...
    • Photodegradation of sparfloxacin and isolation of its degradation products by preparative HPLC 

      Salgado, H.R.N.; Moreno, Paulo Roberto Hrihorowitsch; Braga, A.L.; Schapoval, Elfrides Eva Scherman (2005) [Artigo de periódico]
      Sparfloxacin, a third generation fluoroquinolone derivative,is a potent antibacterial agent active against a wide range ofGram-positive and Gram-negative organisms including Streptococcus pneumoniae, Staphylococcus aureus, ...
    • Photography in pediatric dentistry : basis and applications 

      Werle, Stefanie Bressan; Piva, Fabiane; Assunção, Cristiane Meira; Guimarães, Lizandra Ferrari; Araujo, Fernando Borba de; Coelho de Souza, Fábio Herrmann (2015) [Artigo de periódico]
      There is a lack in the literature regarding the production of digital images in pediatric dentistry. Some technical difficulties on the obtaining the image, such as reduced size of the oral cavity, behavioral aspects and ...
    • Phylloplane yeasts as a source of industrially interesting enzymes 

      Mautone, Juliana Nunes; Landell, Melissa Fontes; Fuentefria, Alexandre Meneghello; Silva, Patrícia Valente da (2010) [Artigo de periódico]
      The objective of this study was to evaluate the phylloplane of tropical plants as a source of yeasts capable of producing industrially relevant enzymes. A total of 446 yeast and yeast-like strains were isolated from the ...
    • Physical activity : do patients infected with HIV practice? How much? A systematic review 

      Trevisol, Fabiana Schuelter; Wolff, Fernando Herz; Alencastro, Paulo Ricardo de; Grigoletti, Shana Souza; Ikeda, Maria Letícia Rodrigues; Brandao, Ajacio Bandeira de Mello; Barcellos, Nêmora Tregnago; Fuchs, Sandra Cristina Pereira Costa (2012) [Artigo de periódico]
      Several studies have suggested that aerobic physical activity is safe and beneficial for HIV-infected adults. However, there is information lacking regarding whether HIV-infected patients practice physical activity and to ...
    • Physical activity guidelines for the brazilian population : development and methods 

      Tenório, Maria Cecília Marinho; Ravagnani, Christianne Coelho; Moraes, Daniel Umpierre de; Andrade, Douglas Roque; Autran, Roseanne; Barros, Mauro Virgílio Gomes; Benedetti, Bertoldo; Cavalcante, Fabiana Vieira Santos Azevedo; Cyrino, Edilson Serpeloni; Dumith, Samuel Carvalho; Florindo, Alex Antonio; Garcia, Leandro Martin Totaro; Mielke, Grégore Iven; Dias, Raphael Mendes Ritti; Magalhães, Lorena Lima; Sandreschi, Paula Fabricio; Manta, Sofia Wolker; Silva, Juliana Rezende Melo da; Silva, Kelly Samara da; Siqueira, Fernando Carlos Vinholes; Hallal, Pedro Curi (2022) [Artigo de periódico]
      Background: This article describes the process and methods used in the development of the first ever Physical Activity Guidelines for the Brazilian Population. Methods: The steering committee established 8 working groups ...