Navegação Ciências da Saúde por Assunto "3’ untranslated region"

Resultados 1-1 de 1

    • Exploring the frequency of a TP53 polyadenylation signal variant in tumor DNA from patients diagnosed with lung adenocarcinomas, sarcomas and uterine leiomyomas 

      Vieira, Igor Araújo; Viola, Guilherme Danielski; Pezzi, Eduarda Heidrich; Kowalski, Thayne Woycinck; Fernandes, Bruna Vieira; Andreis, Tiago Finger; Bom, Natascha; Sonnenstrahl, Giulianna; Rocha, Yasminne Marinho de Araújo; Corrêa, Bruno da Silveira; Donatti, Luiza Mezzomo; Sant'Anna, Gabriela dos Santos; Corleta, Helena von Eye; Brum, Ilma Simoni; Rosset, Clévia; Vianna, Fernanda Sales Luiz; Macedo, Gabriel S.; Palmero, Edenir Inêz; Prolla, Patrícia Ashton (2023) [Artigo de periódico]
      The TP53 3’UTR variant rs78378222 A>C has been detected in different tumor types as a somatic alteration that reduces p53 expression through modification of polyadenylation and miRNA regulation. Its prevalence is not yet ...