Listar Ciencias de la Salud por tema "Synthesis"

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    • Chiral bistacrine analogues : synthesis, cholinesterase inhibitory activity and a molecular modeling approach 

      Lopes, João Paulo Bizarro; Costa, Jessie Sobieski da; Ceschi, Marco Antonio; Goncalves, Carlos Alberto Saraiva; Konrath, Eduardo Luis; Karl, Ana Luiza Martins; Guedes, Isabella Alvim; Dardenne, Laurent Emmanuel (2017) [Artículo de periódico]
      Cholinesterase enzymes are important targets for the therapy of Alzheimer’s disease. Tacrine-based dual binding site cholinesterases inhibitors are potential disease-modifying anti-Alzheimer drug candidates. In the present ...