Navegação Ciências Exatas e da Terra por Assunto "Estresse oxidativo"

Resultados 1-3 de 3

    • Effects of two types of melatonin-loaded nanocapsules with distinct supramolecular structures : Polymeric (NC) and Lipid-Core Nanocapsules (LNC) on bovine embryo culture model 

      Komninou, Eliza Rossi; Remião, Mariana Härter; Lucas, Caroline Gomes; Domingues, William Borges; Basso, Andréa Cristina; Jornada, Denise Soledade; Deschamps, João Carlos; Beck, Ruy Carlos Ruver; Pohlmann, Adriana Raffin; Bordignon, Vilceu; Seixas, Fabiana Kömmling; Campos, Vinicius Farias; Guterres, Silvia Stanisçuaski; Collares, Tiago Veiras (2016) [Artigo de periódico]
      Melatonin has been used as a supplement in culture medium to improve the efficiency of in vitro produced mammalian embryos. Through its ability to scavenge toxic oxygen derivatives and regulate cellular mRNA levels for ...

    • A new strategy for the old challenge of thalidomide : systems biology prioritization of potential immunomodulatory drug (IMiD)-targeted transcription factors 

      Kowalski, Thayne Woycinck; Feira, Mariléa Furtado; Lord, Vinicius Oliveira; Gomes, Julia do Amaral; Giudicelli, Giovanna Câmara; Fraga, Lucas Rosa; Sanseverino, Maria Teresa Vieira; Recamonde-Mendoza, Mariana; Faccini, Lavinia Schuler; Vianna, Fernanda Sales Luiz (2023) [Artigo de periódico]
      Several molecular mechanisms of thalidomide embryopathy (TE) have been investigated, from anti-angiogenesis to oxidative stress to cereblon binding. Recently, it was discovered that thalidomide and its analogs, named ...

    • Peripheral oxidative stress biomarkers in spinocerebellar ataxia type 3/Machado–Joseph disease 

      Assis, Adriano Martimbianco de; Saute, Jonas Alex Morales; Santos, Aline Longoni dos; Haas, Clarissa Branco; Torrez, Vitor Rocco; Brochier, Andressa Wigner; Souza, Gabriele Nunes; Furtado, Gabriel Vasata; Gheno, Tailise Conte; Russo, Aline; Monte, Thais Lampert; Castilhos, Raphael Machado de; Schuh, Artur Francisco Schumacher; Davila, Rui; Donis, Karina Carvalho; Rieder, Carlos Roberto de Mello; Souza, Diogo Onofre Gomes de; Camey, Suzi Alves; Leotti, Vanessa Bielefeldt; Jardim, Laura Bannach; Portela, Luis Valmor Cruz (2017) [Artigo de periódico]
      Objectives: Spinocerebellar ataxia type 3/Machado–Joseph disease (SCA3/MJD) is a polyglutamine disorder with no current disease-modifying treatment. Conformational changes in mutant ataxin-3 trigger different pathogenic ...