Browsing Scientific Production by Subject "6-OHDA"

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    • Intranasal HSP70 administration protects against dopaminergic denervation and modulates neuroinflammatory response in the 6-OHDA rat model 

      Ribeiro, Camila Tiefensee; Peixoto, Daniel Oppermann; Silva, Lucas dos Santos da; Girardi, Carolina Saibro; Brum, Pedro Ozorio; Kessler, Flávio Gabriel Carazza; Somensi, Nauana; Behrens, Luiza Marques Prates; Bittencourt, Reykla Ramon; Soares, Laissa Santos; Silveira, Alexandre Kleber; Oliveira, Jade de; Moreira, Jose Claudio Fonseca; Gasparotto, Juciano; Gelain, Daniel Pens (2021) [Journal article]
      HSP70 is one of the main molecular chaperones involved in the cellular stress response. Besides its chaperone action, HSP70 also modulates the immune response. Increased susceptibility to toxic insults in intra- and ...