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dc.contributor.authorQin, Lupt_BR
dc.contributor.authorConstantin, Jean-Michelpt_BR
dc.contributor.authorNieszkowska, Aniapt_BR
dc.contributor.authorElman, Mariliapt_BR
dc.contributor.authorVieira, Silvia Regina Riospt_BR
dc.contributor.authorRouby, Jean-Jacquespt_BR
dc.date.accessioned2017-01-04T02:27:01Zpt_BR
dc.date.issued2006pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/150426pt_BR
dc.description.abstractIntroduction Positive end-expiratory pressure (PEEP)-induced lung derecruitment can be assessed by a pressure–volume (P– V) curve method or by lung computed tomography (CT). However, only the first method can be used at the bedside. The aim of the study was to compare both methods for assessing alveolar derecruitment after the removal of PEEP in patients with acute lung injury or acute respiratory distress syndrome. Methods P–V curves (constant-flow method) and spiral CT scans of the whole lung were performed at PEEPs of 15 and 0 cmH2O in 19 patients with acute lung injury or acute respiratory distress syndrome. Alveolar derecruitment was defined as the difference in lung volume measured at an airway pressure of 15 cmH2O on P–V curves performed at PEEPs of 15 and 0 cmH2O, and as the difference in the CT volume of gas present in poorly aerated and nonaerated lung regions at PEEPs of 15 and 0 cmH2O. Results Alveolar derecruitments measured by the CT and P–V curve methods were 373 ± 250 and 345 ± 208 ml (p = 0.14), respectively. Measurements by both methods were tightly correlated (R = 0.82, p < 0.0001). The derecruited volume measured by the P–V curve method had a bias of -14 ml and limits of agreement of between -158 and +130 ml in comparison with the average derecruited volume of the CT and P–V curve methods. Conclusion Alveolar derecruitment measured by the CT and P– V curve methods are tightly correlated. However, the large limits of agreement indicate that the P–V curve and the CT method are not interchangeable.en
dc.format.mimetypeapplication/pdf
dc.language.isoengpt_BR
dc.relation.ispartofCritical care. Oxford. Vol. 10, no. 3 (June, 2006), p. 1-10pt_BR
dc.rightsOpen Accessen
dc.subjectSíndrome do desconforto respiratório do adultopt_BR
dc.subjectPressão arterialpt_BR
dc.titleMeasurement of alveolar derecruitment in patients with acute lung injury : computerized tomography versus pressure-volume curvept_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000549370pt_BR
dc.type.originEstrangeiropt_BR


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