Listar Ciencias Biologicas por autor "Karikari, Thomas K."

Mostrando ítems 1-3 de 3

    • Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease 

      Ashton, Nicholas J.; Benedet, Andréa L.; Pascoal, Tharick Ali; Karikari, Thomas K.; Lantero-Rodriguez, Juan; Brum, Wagner Scheeren; Mathotaarachchi, Sulantha Sanjeewa; Therriault, Joseph; Savard, Mélissa; Chamoun, Mira; Stoops, Erik; François, Cindy; Vanmechelen, Eugeen; Gauthier, Serge G.; Zimmer, Eduardo Rigon; Zetterberg, Henrik; Blennow, Kaj; Rosa Neto, Pedro (2022) [Artículo de periódico]
      Background: Phosphorylated tau (p-tau) epitopes in cerebrospinal fluid (CSF) are accurate biomarkers for a pathological and clinical diagnosis of Alzheimer's disease (AD) and are seen to be increased in preclinical stage ...

    • The accuracy and robustness of plasma biomarker models for amyloid PET positivity 

      Benedet, Andréa L.; Brum, Wagner Scheeren; Hansson, Oskar; Karikari, Thomas K.; Zimmer, Eduardo Rigon; Zetterberg, Henrik; Blennow, Kaj; Ashton, Nicholas J. (2022) [Artículo de periódico]
      Background: Plasma biomarkers for Alzheimer’s disease (AD) have broad potential as screening tools in primary care and disease-modifying trials. Detecting elevated amyloid-β (Aβ) pathology to support trial recruitment or ...

    • A three-range approach enhances the prognostic utility of CSF biomarkers in Alzheimer's disease 

      Brum, Wagner Scheeren; De Bastiani, Marco Antônio; Bieger, Andrei; Therriault, Joseph; Souza, João Pedro Ferrari; Benedet, Andréa L.; Saha-Chaudhuri, Paramita; Souza, Diogo Onofre Gomes de; Ashton, Nicholas J.; Zetterberg, Henrik; Pascoal, Tharick Ali; Karikari, Thomas K.; Blennow, Kaj; Rosa Neto, Pedro; Zimmer, Eduardo Rigon; Alzheimer’s Disease Neuroimaging Initiative (2022) [Artículo de periódico]
      Introduction: Alzheimer's disease consensus recommends biomarker dichotomization, a practice with well-described clinical strengths and methodological limitations. Although neuroimaging studies have explored alternative ...