Browsing Biological Sciences by Author "Tuana, Florencia María Barbé"

Now showing items 1-3 of 3

    • cGAS-STING pathway as a potential trigger of immunosenescence and inflammaging 

      Schmitz, Carine Raquel Richter; Maurmann, Rafael Moura; Guma, Fátima Theresinha Costa Rodrigues; Bauer, Moises Evandro; Tuana, Florencia María Barbé (2023) [Journal article]
      Aging is associated with an increased incidence of autoimmune diseases, despite the progressive decline of immune responses (immunosenescence). This apparent paradox can be explained by the age-related chronic low-grade ...

    • Eotaxin-1/CCL11 promotes cellular senescence in human-derived fibroblasts through pro-oxidant and pro-inflammatory pathways 

      Lavandoski, Patricia; Lima, Vinícius Pierdoná; Maurmann, Rafael Moura; Grun, Lucas Kich; Guma, Fátima Theresinha Costa Rodrigues; Tuana, Florencia María Barbé (2023) [Journal article]
      Introduction: Eotaxin-1/CCL11 is a pivotal chemokine crucial for eosinophil homing to the lungs of asthmatic patients. Recent studies also suggest that CCL11 is involved in the aging process, as it is upregulated in elderly, ...

    • PseudoCell : a multivalued logical regulatory network to investigate premature senescence dynamics and heterogeneity 

      Lima, Vinícius Pierdoná; Lavandoski, Patricia; Maurmann, Rafael Moura; Borges, Guilherme Antonio; Mombach, Jose Carlos Merino; Guma, Fátima Theresinha Costa Rodrigues; Tuana, Florencia María Barbé (2025) [Journal article]
      Purpose: Premature cellular senescence is a pivotal process in aging and age-related diseases, triggered by various stressors. However, this is not a homogeneous phenotype, but a heterogeneous cellular state composed of ...