Now showing items 1-20 of 2234

    • 22q11.2 duplication and congenital heart defects 

      Rosa, Rafael Fabiano Machado; Zen, Paulo Ricardo Gazzola; Ricachinevsky, Claudia Pires; Pilla, Carlo Benatti; Pereira, Vera Lúcia Berenstein; Roman, Tatiana; Garcia, Marileila Varella; Paskulin, Giorgio Adriano (2009) [Journal article]
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    • 37 years of scientific activity in a Biochemistry Department in Brazil – patterns of growth and factors leading to increased productivity 

      Gomes, Urubatã Estivalet; Oliveira, Diogo Losch de; Calabró, Luciana; Amaral, Olavo Bohrer; Souza, Diogo Onofre Gomes de; Wofchuk, Susana Tchernin (2011) [Journal article]
      Scientific activity in Brazil has experienced an accelerated growth in the past decades, with an increase in productivity that greatly surpasses the international average. This growth has occurred mostly at the expense of ...
    • ABCB1 C1236T, G2677T/A and C3435T polymorphisms in systemic lupus erythematosus patients 

      Gonzalez, Tatiana Pereira; Mucenic, Tamara; Brenol, João Carlos Tavares; Xavier, Ricardo Machado; Schiengold, Marion; Chies, Jose Artur Bogo (2008) [Journal article]
      P-glycoprotein (Pgp), the ABCB1 gene product, acts as an efflux pump that transports a large variety of substrates and is a mechanism of cell protection against xenobiotics. An increasing number of studies have shown that ...
    • Absence of A3Z3-related hypermutations in the env and vif proviral genes in FIV naturally infected cats 

      Cano Ortiz, Lucía; Junqueira, Dennis Maletich; Comerlato, Juliana; Zani, André Luis da Silva; Costa, Cristina Santos da; Roehe, Paulo Michel; Franco, Ana Claudia (2018) [Journal article]
      Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) proteins comprise an important family of restriction factors that produce hypermutations on proviral DNA and are able to limit virus replication. ...
    • Absence of sibutramine effect on spontaneous anxiety in rats 

      Frassetto, Silvana Soriano; Alves, Isis Orestes; Santos, Marislane Marília; Schmidt, Ana Eduarda Stein; Lopes, Janaína Jardim; Oliveira, Paulo A.; Vinagre, Anapaula Sommer; Pereira, Patricia (2010) [Journal article]
      A sibutramina tem sido descrita como um fármaco recomendado para o tratamento da obesidade, uma vez que tem a capacidade de inibir a recaptação de serotonina e noradrenalina no sistema nervoso central, aumentando assim o ...
    • Abundance and richness of Arctiinae moths throughout the night in a Cerrado area 

      Santos, Carolina Moreno dos; Barbosa, Ângela S.; Ferro, Viviane G. (2021) [Journal article]
      The main goal of this work was to investigate how the abundance and richness of Arctiinae moths varies over time, during the night. Specifically, we analyzed the following questions: (1) Is there a relationship between ...
    • Abundance of Conepatus chinga (Carnivora, Mephitidae) and other medium-sized mammals in grasslands of southern Brazil 

      Kasper, Carlos Benhur; Bastazini, Vinícius Augusto Galvão; Soares, José Bonifácio Garcia; Freitas, Thales Renato Ochotorena de (2012) [Journal article]
      Entre janeiro de 2007 e dezembro de 2010 a abundância de mamíferos de médio porte foi estudada, com especial ênfase no zorrilho Conepatus chinga (Molina, 1782) em quatro locais no sul do Brasil. Neste estudo, foi utilizada ...
    • Ação de antissépticos e desinfetantes de uso doméstico sobre Enterococcus sp. isolados do arroio Dilúvio, RS, Brasil 

      Bandeira, Natalia Costantin; Garbinatto, Gisele Nachtigall; Mann, Michele Bertoni; Frazzon, Ana Paula Guedes (2019) [Journal article]
      O arroio Dilúvio, localizado em uma área central de Porto Alegre, recebe diariamente lixo e esgoto doméstico de vários bairros da cidade, que sem o tratamento adequado poderão ser fonte de diferentes microrganismos, entre ...
    • Access to treatment for phenylketonuria by judicial means in Rio Grande do Sul, Brazil 

      Trevisan, Luciano Mangueira; Nalin, Tatiéle; Tonon, Tássia; Veiga, Lauren; Vargas, Paula; Krug, Bárbara Côrrea; Leivas, Paulo Gilberto Cogo; Schwartz, Ida Vanessa Doederlein (2015) [Journal article]
      Treatment of phenylketonuria (PKU) includes the use of a metabolic formula which should be provided free of charge by the Unified Health System (SUS). This retrospective, observational study sought to characterize judicial ...
    • Acciones para la salud general y bucal con pacientes psiquiátricos en talleres terapéuticos 

      Copês, Liliana Ganciné; Figueiredo, Márcia Cançado; Silva, Katia Valenca Correia Leandro da (2011) [Journal article]
      De acuerdo con el Ministerio de Salud de Brasil, el 3% de la población general presenta trastornos psiquiátricos severos y persistentes y un 12% necesita de algún tipo de tratamiento psiquiátrico, sea continuo o eventual. ...
    • Acidúrias orgânicas : diagnóstico em pacientes de alto risco no Brasil 

      Wajner, Moacir; Barschak, Alethea Gatto; Luft, Ana Paula; Pires, Ricardo Flores; Grillo, Eugênio; Lohr, Alfredo; Funayama, Carolina Araújo Rodrigues; Sanseverino, Maria Teresa Vieira; Giugliani, Roberto; Vargas, Carmen Regla (2001) [Journal article]
      Objetivo: o objetivo deste trabalho foi o de verificar a prevalência das acidúrias orgânicas em pacientes brasileiros de alto risco. Métodos: técnicas laboratoriais para a detecção e quantificação de ácidos orgânicos por ...
    • Acoustic measures of Brazilian transgender women's voices : a case–control study 

      Villas-Bôas, Anna Paula de Sá; Schwarz, Karine; Fontanari, Anna Martha Vaitses; Costa, Angelo Brandelli; Silva, Dhiordan Cardoso da; Schneider, Maiko Abel; Cielo, Carla Aparecida; Spritzer, Poli Mara; Lobato, Maria Inês Rodrigues (2021) [Journal article]
      Objective: This study aims to compare the acoustic vocal analysis results of a group of transgender women relative to those of cisgender women. Methods: Thirty transgender women between the ages of 19 and 52 years old ...
    • Actividad antimicrobiana de aceite esencial de Origanum vulgare L. ante bacterias aisladas en leche de bovino 

      Oyarzabal, Marta Elaine Bastos; Schuch, Luiz Filipe Damé; Prestes, Luciana de Souza; Schiavon, Diane Bender Almeida; Rodrigues, Maria Regina Alves; Mello, Joao Roberto Braga de (2011) [Journal article]
      Introducción: la mastitis bovina es el mayor problema en la producción lechera, causada principalmente por bacterias grampositivas. La búsqueda de principios activos que actúen en esos microrganismos es creciente, sobre ...
    • Activity of the antimicrobial peptide P34 against bovine alphaherpesvirus type 1 

      Castro, Clarissa Caetano de; Silva, Débora Scopel e; Costa, Géssica Aracéli; Fischer, Geferson; Vargas, Gilberto D`Avila; Brandelli, Adriano; Lima, Marcelo de; Motta, Amanda de Souza da; Hübner, Sílvia de Oliveira (2017) [Journal article]
      Previous studies have demonstrated the antimicrobial activity of the peptide P34. In this study, the antiviral potential of P34 and the in vitro mechanism of action were investigated against bovine alphaherpesvirus type 1 ...
    • Acute consumption of bordo grape juice and wine improves serum antioxidant status in healthy individuals and inhibits reactive oxygen species production in human neuron-like cells 

      Copetti, Cristiane; Franco, Fernanda Wouters; Machado, Eduarda da Rosa; Soquetta, Marcela Bromberger; Quatrin, Andréia; Ramos, Vitor de Miranda; Moreira, Jose Claudio Fonseca; Emanuelli, Tatiana; Sautter, Cláudia Kaehler; Penna, Neidi Garcia (2018) [Journal article]
      Few studies investigated the biological effects of American grape cultivars. We investigated the metabolic response after acute consumption of grape juice or wine from Bordo grapes (Vitis labrusca) in a placebo-controlled ...
    • Acute liver failure induces glial reactivity, oxidative stress and impairs brain energy metabolism in rats 

      Guazzelli, Pedro Arend; Santos, Giordano Fabricio Cittolin; Martins, Leo Anderson Meira; Grings, Mateus; Nonose, Yasmine; Lazzarotto, Gabriela; Nogara, Daniela Albugeri; Silva, Jussemara Souza da; Fontella, Fernanda Urruth; Wajner, Moacir; Leipnitz, Guilhian; Souza, Diogo Onofre Gomes de; Assis, Adriano Martimbianco de (2020) [Journal article]
      Acute liver failure (ALF) implies a severe and rapid liver dysfunction that leads to impaired liver metabolism and hepatic encephalopathy (HE). Recent studies have suggested that several brain alterations such as astrocytic ...
    • ADCK2 haploinsuciency reduces mitochondrial lipid oxidation and causes myopathy associated with CoQ deficiency 

      Matté, Cristiane; Vázquez-Fonseca, Luis; Navas, Plácido (2019) [Journal article]
      Fatty acids and glucose are the main bioenergetic substrates in mammals. Impairment of mitochondrial fatty acid oxidation causes mitochondrial myopathy leading to decreased physical performance. Here, we report that haploinsu ...
    • Aderência bacteriana in vitro a lentes intra-oculares de polimetilmetacrilato e de silicone 

      Locatelli, Claudete Inês; Hidalgo, Gelsa Edith Navarro; Kwitko, Sergio; Simonetti, Amauri Braga (2004) [Journal article]
      Objetivos: Verificar a aderência bacteriana a lentes intra-oculares de silicone e de polimetilmetacrilato como possível fator de risco no desenvolvimento de endoftalmite pós-operatória, utilizando-se um modelo in vitro com ...
    • Adesão a listas de medicamentos essenciais em municípios de três estados brasileiros 

      Dal Pizzol, Tatiane da Silva; Trevisol, Daisson José; Heineck, Isabela; Flores, Liziane Maahs; Camargo, Aline Lins; Koenig, Alvaro; Torres, Iraci Lucena da Silva; Kadri, Mônica Cristina Toffoli; Monreal, Maria Tereza Ferreira Duenhas; Melo, Adriana Mary Mestriner Felipe de; Ferreira, Maria Beatriz Cardoso (2010) [Journal article]
      Este estudo comparou as Relações Municipais de Medicamentos Essenciais (REMUME), analisou a adesão dos prescritores e a disponibilidade de medicamentos essenciais em unidades de saúde vinculadas ao Sistema Único de Saúde ...
    • Adipose tissue of female Wistar rats respond to Ilex paraguariensis treatment after ovariectomy surgery 

      Rocha, Débora Santos; Model, Jorge Felipe Argenta; Dentz, Maiza Cristina Von; Maschio, Jéssica; Ohlweiler, Renata Victória da Cruz; Lima, Matheus Vieira; Souza, Samir Kahl de; Sarapio, Elaine Renner; Vogt, Éverton Lopes; Waszczuk, Mairique; Martiny, Simony; Bassani, Valquiria Linck; Kucharski, Luiz Carlos Rios (2021) [Journal article]
      Background and aim: Metabolic disturbances are known for their increasing epidemiological importance. Ilex paraguariensis presents a potential option for mitigating lipid metabolism imbalance. However, most of the literature ...