Now showing items 1-20 of 2831

    • 1,25-dihydroxyvitamin D3 exerts neuroprotective effects in an ex vivo model of mild hyperhomocysteinemia 

      Santos, Aline Longoni dos; Kolling, Janaína; Santos, Tiago Marcon dos; Santos, João Paulo Almeida dos; Silva, Jussemara Souza da; Petenuzzo, Letícia Ferreira; Goncalves, Carlos Alberto Saraiva; Assis, Adriano Martimbianco de; Quincozes-Santos, André; Wyse, Angela Terezinha de Souza (2016) [Journal article]
      Elevated plasma homocysteine (Hcy) levels have been detected in patients with various neurodegenerative conditions. Studies of brain tissue have revealed that hyperhomocysteinemia may impair energy metabolism, resulting ...
    • 22q11.2 duplication and congenital heart defects 

      Rosa, Rafael Fabiano Machado; Zen, Paulo Ricardo Gazzola; Ricachinevsky, Claudia Pires; Pilla, Carlo Benatti; Pereira, Vera Lúcia Berenstein; Roman, Tatiana; Garcia, Marileila Varella; Paskulin, Giorgio Adriano (2009) [Journal article]
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    • 37 years of scientific activity in a Biochemistry Department in Brazil – patterns of growth and factors leading to increased productivity 

      Gomes, Urubatã Estivalet; Oliveira, Diogo Losch de; Calabró, Luciana; Amaral, Olavo Bohrer; Souza, Diogo Onofre Gomes de; Wofchuk, Susana Tchernin (2011) [Journal article]
      Scientific activity in Brazil has experienced an accelerated growth in the past decades, with an increase in productivity that greatly surpasses the international average. This growth has occurred mostly at the expense of ...
    • ABCB1 C1236T, G2677T/A and C3435T polymorphisms in systemic lupus erythematosus patients 

      Gonzalez, Tatiana Pereira; Mucenic, Tamara; Brenol, João Carlos Tavares; Xavier, Ricardo Machado; Schiengold, Marion; Chies, Jose Artur Bogo (2008) [Journal article]
      P-glycoprotein (Pgp), the ABCB1 gene product, acts as an efflux pump that transports a large variety of substrates and is a mechanism of cell protection against xenobiotics. An increasing number of studies have shown that ...
    • Absence of A3Z3-related hypermutations in the env and vif proviral genes in FIV naturally infected cats 

      Cano Ortiz, Lucía; Junqueira, Dennis Maletich; Comerlato, Juliana; Zani, André Luis da Silva; Costa, Cristina Santos da; Roehe, Paulo Michel; Franco, Ana Claudia (2018) [Journal article]
      Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3; A3) proteins comprise an important family of restriction factors that produce hypermutations on proviral DNA and are able to limit virus replication. ...
    • Absence of sibutramine effect on spontaneous anxiety in rats 

      Frassetto, Silvana Soriano; Alves, Isis Orestes; Santos, Marislane Marília; Schmidt, Ana Eduarda Stein; Lopes, Janaína Jardim; Oliveira, Paulo A.; Vinagre, Anapaula Sommer; Pereira, Patricia (2010) [Journal article]
      A sibutramina tem sido descrita como um fármaco recomendado para o tratamento da obesidade, uma vez que tem a capacidade de inibir a recaptação de serotonina e noradrenalina no sistema nervoso central, aumentando assim o ...
    • Abundance and richness of Arctiinae moths throughout the night in a Cerrado area 

      Santos, Carolina Moreno dos; Barbosa, Ângela S.; Ferro, Viviane Gianluppi (2021) [Journal article]
      The main goal of this work was to investigate how the abundance and richness of Arctiinae moths varies over time, during the night. Specifically, we analyzed the following questions: (1) Is there a relationship between ...
    • Abundance of Conepatus chinga (Carnivora, Mephitidae) and other medium-sized mammals in grasslands of southern Brazil 

      Kasper, Carlos Benhur; Bastazini, Vinícius Augusto Galvão; Soares, José Bonifácio Garcia; Freitas, Thales Renato Ochotorena de (2012) [Journal article]
      Entre janeiro de 2007 e dezembro de 2010 a abundância de mamíferos de médio porte foi estudada, com especial ênfase no zorrilho Conepatus chinga (Molina, 1782) em quatro locais no sul do Brasil. Neste estudo, foi utilizada ...
    • Ação de antissépticos e desinfetantes de uso doméstico sobre Enterococcus sp. isolados do arroio Dilúvio, RS, Brasil 

      Bandeira, Natalia Costantin; Garbinatto, Gisele Nachtigall; Mann, Michele Bertoni; Frazzon, Ana Paula Guedes (2019) [Journal article]
      O arroio Dilúvio, localizado em uma área central de Porto Alegre, recebe diariamente lixo e esgoto doméstico de vários bairros da cidade, que sem o tratamento adequado poderão ser fonte de diferentes microrganismos, entre ...
    • Access to treatment for phenylketonuria by judicial means in Rio Grande do Sul, Brazil 

      Trevisan, Luciano Mangueira; Nalin, Tatiéle; Tonon, Tássia; Veiga, Lauren; Vargas, Paula; Krug, Bárbara Côrrea; Leivas, Paulo Gilberto Cogo; Schwartz, Ida Vanessa Doederlein (2015) [Journal article]
      Treatment of phenylketonuria (PKU) includes the use of a metabolic formula which should be provided free of charge by the Unified Health System (SUS). This retrospective, observational study sought to characterize judicial ...
    • Acciones para la salud general y bucal con pacientes psiquiátricos en talleres terapéuticos 

      Copês, Liliana Ganciné; Figueiredo, Márcia Cançado; Silva, Katia Valenca Correia Leandro da (2011) [Journal article]
      De acuerdo con el Ministerio de Salud de Brasil, el 3% de la población general presenta trastornos psiquiátricos severos y persistentes y un 12% necesita de algún tipo de tratamiento psiquiátrico, sea continuo o eventual. ...
    • Acidúrias orgânicas : diagnóstico em pacientes de alto risco no Brasil 

      Wajner, Moacir; Barschak, Alethea Gatto; Luft, Ana Paula; Pires, Ricardo Flores; Grillo, Eugênio; Lohr, Alfredo; Funayama, Carolina Araújo Rodrigues; Sanseverino, Maria Teresa Vieira; Giugliani, Roberto; Vargas, Carmen Regla (2001) [Journal article]
      Objetivo: o objetivo deste trabalho foi o de verificar a prevalência das acidúrias orgânicas em pacientes brasileiros de alto risco. Métodos: técnicas laboratoriais para a detecção e quantificação de ácidos orgânicos por ...
    • Acoustic measures of Brazilian transgender women's voices : a case–control study 

      Villas-Bôas, Anna Paula de Sá; Schwarz, Karine; Fontanari, Anna Martha Vaitses; Costa, Angelo Brandelli; Silva, Dhiordan Cardoso da; Schneider, Maiko Abel; Cielo, Carla Aparecida; Spritzer, Poli Mara; Lobato, Maria Inês Rodrigues (2021) [Journal article]
      Objective: This study aims to compare the acoustic vocal analysis results of a group of transgender women relative to those of cisgender women. Methods: Thirty transgender women between the ages of 19 and 52 years old ...
    • Activation of adenosine A1 receptors alters behavioral and biochemical parameters in hyperthyroid rats 

      Bruno, Alessandra Nejar; Fontella, Fernanda Urruth; Bonan, Carla Denise; Chaves, Maria Luiza Morais Barreto de; Dalmaz, Carla; Sarkis, João José Freitas (2006) [Journal article]
      Adenosine acting on A1 receptors has been related with neuroprotective and neuromodulatory actions, protection against oxidative stress and decrease of anxiety and nociceptive signaling. Previous studies demonstrated an ...
    • Actividad antimicrobiana de aceite esencial de Origanum vulgare L. ante bacterias aisladas en leche de bovino 

      Oyarzabal, Marta Elaine Bastos; Schuch, Luiz Filipe Damé; Prestes, Luciana de Souza; Schiavon, Diane Bender Almeida; Rodrigues, Maria Regina Alves; Mello, Joao Roberto Braga de (2011) [Journal article]
      Introducción: la mastitis bovina es el mayor problema en la producción lechera, causada principalmente por bacterias grampositivas. La búsqueda de principios activos que actúen en esos microrganismos es creciente, sobre ...
    • Activity and expression of ecto-5'-nucleotidase/CD73 are increased by thyroid hormones in vascular smooth muscle cells 

      Tamajusuku, Alessandra Sayuri Kikuchi; Sepúlveda, Maria Alicia Carrillo; Braganhol, Elizandra; Wink, Marcia Rosangela; Sarkis, João José Freitas; Chaves, Maria Luiza Morais Barreto de; Battastini, Ana Maria Oliveira (2006) [Journal article]
      Extracellular nucleotides ATP, ADP, AMP and adenosine are well known signaling molecules of the cardiovascular system that are involved in several physiological processes: cell proliferation, platelet aggregation, inflammatory ...
    • Activity and expression of ecto-nucleotide pyrophosphate/phosphodiesterases in a hepatic stellate cell line 

      Andrade, Claudia Marlise Balbinotti; Wink, Marcia Rosangela; Margis, Rogerio; Borojevic, Radovan; Battastini, Ana Maria Oliveira; Guma, Fátima Theresinha Costa Rodrigues (2009) [Journal article]
      Nucleotides and nucleosides represent an important and ubiquitous class of molecules that interact with specific receptors, regulate a variety of activities within the liver, and play a role in the pathogenesis of hepatic ...
    • Activity of the antimicrobial peptide P34 against bovine alphaherpesvirus type 1 

      Castro, Clarissa Caetano de; Silva, Débora Scopel e; Costa, Géssica Aracéli; Fischer, Geferson; Vargas, Gilberto D`Avila; Brandelli, Adriano; Lima, Marcelo de; Motta, Amanda de Souza da; Hübner, Sílvia de Oliveira (2017) [Journal article]
      Previous studies have demonstrated the antimicrobial activity of the peptide P34. In this study, the antiviral potential of P34 and the in vitro mechanism of action were investigated against bovine alphaherpesvirus type 1 ...
    • Acute and chronic hypermethioninemia alter Na+,K+-ATPase activity in rat hippocampus : prevention by antioxidants 

      Stefanello, Francieli Moro; Ferreira, Andréa Gisiane Kurek; Pereira, Talita Carneiro Brandao; Cunha, Maira Jaqueline da; Bonan, Carla Denise; Bogo, Mauricio Reis; Wyse, Angela Terezinha de Souza (2011) [Journal article]
      In the current study we initially investigated the influence of antioxidants (vitamins E plus C) on the effect mediated by acute and chronic administration of methionine (Met) on Na+,K+-ATPase activity in rat hippocampus. ...