Browsing Health Sciences by Subject "Nanocápsulas"
Now showing items 1-6 of 6
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Degradação e estabilização do diclofenaco em nanocápsulas poliméricas
(2004) [Journal article]The parameters which affect the degradation and stabilization of diclofenac in suspensions of nanocapsules and of the corresponding spray-dried powders were investigated. Formulations were subjected to 14 months of storage ... -
Hydrogels containing redispersible spray-dried melatonin-loaded nanocapsules : a formulation for transdermal-controlled delivery
(2012) [Journal article]The aim of the present study was to develop a transdermal system for controlled delivery of melatonin combining three strategies: nanoencapsulation of melatonin, drying of melatonin-loaded nanocapsules, and incorporation ... -
LC-MS/MS method applied to preclinical pharmacokinetic investigation of olanzapine-loaded lipid-core nanocapsules
(2014) [Journal article]In spite of different methods reported in the literature to determine olanzapine in biological fluids, all of them used high volumes of plasma. Therefore, the purpose of this paper was to develop an LC-MS/MS method using ... -
Nanostructured systems containing an essential oil : protection against volatilization
(2011) [Journal article]The goal of this study was to evaluate the feasibility of preparing nanocapsules and nanoemulsions using tea tree oil as oily phase aiming to protect its volatilization. The nanostructures presented nanometric mean size ... -
Nanostructured systems containing rutin: in vitro antioxidant activity and photostability studies
(2010) [Journal article]The improvement of the rutin photostability and its prolonged in vitro antioxidant activity were studied by means of its association with nanostructured aqueous dispersions. Rutin-loaded nanocapsules and rutin-loaded ... -
The antiproliferative effect of indomethacin-loaded lipid-core nanocapsules in glioma cells is mediated by cell cycle regulation, differentiation, and inhibition of survival patheways
(2013) [Journal article]Despite recent advances in radiotherapy, chemotherapy, and surgical techniques, glioblastoma multiforme (GBM) prognosis remains dismal. There is an urgent need for new therapeutic strategies. Nanoparticles of biodegradable ...
