Now showing items 1-5 of 5

    • Adsorção de oligonucleotídeos em nanoemulsões obtidas por emulsificação espontânea 

      Martini, Érico; Carvalho, Edison Luis Santana; Teixeira, Helder Ferreira; Leão, Fabiana; Oliveira, Mônica Cristina de (2007) [Journal article]
      This paper describes the adsorption of an oligothymidylate (pdT16) on nanoemulsions obtained by spontaneous emulsification procedures. Formulations were composed by medium chain triglycerides, egg lecithin, glycerol, water ...
    • Factors influencing transfection efficiency of pIDUA/nanoemulsion complexes in a mucopolysaccharidosis type I murine model 

      Fraga, Michelle; Carvalho, Talita Giacomet de; Bidone, Juliana; Schuh, Roselena Silvestri; Matte, Ursula da Silveira; Teixeira, Helder Ferreira (2017) [Journal article]
      Mucopolysaccharidosis type I (MPS I) is an autosomal disease caused by alpha-l-iduronidase (IDUA) deficiency. This study used IDUA knockout mice as a model to evaluate whether parameters such as dose of plasmid and time ...
    • Nanoemulsões como sistemas de liberação parenteral de fármacos 

      Bruxel, Fernanda; Laux, Manoela; Wild, Luisa Bartmann; Fraga, Michelle; Koester, Leticia Scherer; Teixeira, Helder Ferreira (2012) [Journal article]
      Lipid nanoemulsions have recently been proposed as parenteral delivery systems for poorly-soluble drugs. These systems consist of nanoscale oil/water dispersions stabilized by an appropriate surfactant system in which the ...
    • Nanostructured systems containing an essential oil : protection against volatilization 

      Flores, Fernanda Cramer; Ribeiro, Roseane Fagundes; Ourique, Aline Ferreira; Rolim, Clarice Madalena Bueno; Silva, Cristiane de Bona da; Pohlmann, Adriana Raffin; Beck, Ruy Carlos Ruver; Guterres, Silvia Stanisçuaski (2011) [Journal article]
      The goal of this study was to evaluate the feasibility of preparing nanocapsules and nanoemulsions using tea tree oil as oily phase aiming to protect its volatilization. The nanostructures presented nanometric mean size ...
    • Validation of a spectrophotometric method to estimate the adsorption on nanoemulsions of an antimalarial oligonucleotide 

      Bruxel, Fernanda; Guterres, Silvia Stanisçuaski; Teixeira, Helder Ferreira (2011) [Journal article]
      This study describes the validation of a spectrophotometric method to estimate oligonucleotides association with cationic nanoemulsions. Phosphodiester and phosphorothioate oligonucleotides targeting Plasmodium falciparum ...