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dc.contributor.authorVianna, Monica Ryff Moreira Rocapt_BR
dc.contributor.authorIzquierdo, Luciana Adrianapt_BR
dc.contributor.authorBarros, Daniela Martipt_BR
dc.contributor.authorWalz, Rogerpt_BR
dc.contributor.authorMedina, Jorge Horáciopt_BR
dc.contributor.authorIzquierdo, Ivan Antoniopt_BR
dc.date.accessioned2012-03-20T01:21:03Zpt_BR
dc.date.issued2000pt_BR
dc.identifier.issn0001-3765pt_BR
dc.identifier.urihttp://hdl.handle.net/10183/37594pt_BR
dc.description.abstractSince William James (1890) first distinguished primary from secondary memory, equivalent to short- and longterm memory, respectively, it has been assumed that short-term memory processes are in charge of cognition while long-term memory is being consolidated. From those days a major question has been whether shortterm memory is merely a initial phase of long-term memory, or a separate phenomena. Recent experiments have shown that many treatments with specific molecular actions given into the hippocampus and related brain areas after one-trial avoidance learning can effectively cancel short-term memory without affecting long-term memory formation. This shows that short-term memory and long-term memory involve separate mechanisms and are independently processed. Other treatments, however, influence both memory types similarly, suggesting links between both at the receptor and at the post-receptor level, which should not be surprising as they both deal with nearly the same sensorimotor representations. This review examines recent advances in short- and long-term memory mechanisms based on the effect of intra-hippocampal infusion of drugs acting upon neurotransmitter and signal transduction systems on both memory types.en
dc.format.mimetypeapplication/pdfpt_BR
dc.language.isoengpt_BR
dc.relation.ispartofAnais da academia brasileira de ciencias. Rio de Janeiro. Vol. 72, n. 3 (2000), p. 353-364pt_BR
dc.rightsOpen Accessen
dc.subjectShort-term memoryen
dc.subjectBioquímicapt_BR
dc.subjectLong-term memoryen
dc.subjectHippocampusen
dc.subjectPKAen
dc.subjectPKCen
dc.subjectMAPKen
dc.titleShort- and long-term memory : differential involvement of neurotransmitter systems and signal transduction cascadespt_BR
dc.typeArtigo de periódicopt_BR
dc.identifier.nrb000311140pt_BR
dc.type.originNacionalpt_BR


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