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Is SAPS 3 better than APACHE II at predicting mortality in critically ill transplant patients?

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Is SAPS 3 better than APACHE II at predicting mortality in critically ill transplant patients?

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Título Is SAPS 3 better than APACHE II at predicting mortality in critically ill transplant patients?
Autor Oliveira, Vanessa Martins de
Brauner, Janete Salles
Rodrigues Filho, Edison Moraes
Susin, Ruth Guimarães de Almeida
Draghetti, Viviani
Bolzan, Simone Tasqueto
Vieira, Silvia Regina Rios
Abstract OBJECTIVES: This study compared the accuracy of the Simplified Acute Physiology Score 3 with that of Acute Physiology and Chronic Health Evaluation II at predicting hospital mortality in patients from a transplant intensive care unit. METHOD: A total of 501 patients were enrolled in the study (152 liver transplants, 271 kidney transplants, 54 lung transplants, 24 kidney-pancreas transplants) between May 2006 and January 2007. The Simplified Acute Physiology Score 3 was calculated using the global equation (customized for South America) and the Acute Physiology and Chronic Health Evaluation II score; the scores were calculated within 24 hours of admission. A receiver-operating characteristic curve was generated, and the area under the receiver-operating characteristic curve was calculated to identify the patients at the greatest risk of death according to Simplified Acute Physiology Score 3 and Acute Physiology and Chronic Health Evaluation II scores. The Hosmer-Lemeshow goodness-of-fit test was used for statistically significant results and indicated a difference in performance over deciles. The standardized mortality ratio was used to estimate the overall model performance. RESULTS: The ability of both scores to predict hospital mortality was poor in the liver and renal transplant groups and average in the lung transplant group (area under the receiver-operating characteristic curve = 0.696 for Simplified Acute Physiology Score 3 and 0.670 for Acute Physiology and Chronic Health Evaluation II). The calibration of both scores was poor, even after customizing the Simplified Acute Physiology Score 3 score for South America. CONCLUSIONS: The low predictive accuracy of the Simplified Acute Physiology Score 3 and Acute Physiology and Chronic Health Evaluation II scores does not warrant the use of these scores in critically ill transplant patients.
Contido em Clinics (São Paulo). São Paulo. Vol. 68, n. 2 (fev. 2013), p. 153-158
Assunto Mortalidade
Pontuação de propensão
Transplante de fígado
Transplante de pulmão
Transplante de rim
[en] Critical care patients
[en] Kidney transplantation
[en] Liver transplantation
[en] Lung transplantation
[en] PACHE
[en] SAPS
Origem Nacional
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/108655
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