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A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay

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A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay

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Título A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay
Autor Oliveira, Maria Laura Cosetti
Wagner, Vivian Petersen
Sant'Ana Filho, Manoel
Carrard, Vinícius Coelho
Hugo, Fernando Neves
Martins, Manoela Domingues
Abstract The aim of this study was to evaluate the demographic, clinical, and therapeutic characteristics and predictive factors of poor prognosis in patients with primary oral squamous cell carcinoma (OSCC) in Uruguay. Medical records of patients with the diagnosis of primary OSCC treated between 2000 and 2010 in Uruguayan public hospitals were selected. Data on demographic characteristics, risk factors, clinical features, treatment, and outcome were collected. Associations of independent variables with outcomes were assessed using Pearson chi-squared and Fisher’s tests. Of 200 patients with OSCC, 79.4% were men (3.8:1 male:female ratio), with a mean age of 60.75 ± 11.26 years. Tobacco and alcohol consumption were reported by 85.3% and 63.5% of patients, respectively. The most commonly affected location was the tongue (42.5%), with lesions exhibiting ulcerous aspects in 87.9% of cases and pain at the time of diagnosis in 70.4% of cases. One hundred sixty-one (82.1%) patients had advanced-stage (III/IV) OSCC. Surgery was the most common treatment option, and the overall 5-year survival rate was 58.5%. Univariate analysis showed that the predictors of poor prognosis were clinical aspect, size, regional metastasis, clinical stage, and treatment. In Uruguay, OSCC is diagnosed late, which is associated with a low survival rate. Educational and preventive measures and investment to improve early diagnosis should be undertaken.
Contido em Brazilian oral research. São Paulo. Vol. 29, no. 1 (2015), p. 1-8
Assunto Carcinoma de células escamosas
Doenças da boca
Saúde pública
Uruguai
[en] Delayed Diagnosis
[en] Epidemiology
[en] Mouth Neoplasms
[en] Prognosis
Origem Nacional
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/131736
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