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Mortality among patients with tuberculosis requiring intensive care: a retrospective cohort study

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Mortality among patients with tuberculosis requiring intensive care: a retrospective cohort study

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Título Mortality among patients with tuberculosis requiring intensive care: a retrospective cohort study
Autor Silva, Denise Rossato
Menegotto, Diego Milan
Schulz, Luis Fernando
Gazzana, Marcelo Basso
Dalcin, Paulo de Tarso Roth
Abstract Background: To describe the characteristics of patients with tuberculosis (TB) requiring intensive care and to identify the factors that predicts in-hospital mortality in a city of a developing country with intermediate-to-high TB endemicity. Methods: We conducted a retrospective, cohort study, between November 2005 and November 2007. The patients with TB requiring intensive care were included. Predictors of mortality were assessed. The primary outcome was the in-hospital mortality. Results: During the study period, 67 patients with TB required intensive care. Of them, 62 (92.5%) had acute respiratory failure and required mechanical ventilation. Forty-four (65.7%) patients died. Coinfection with human immunodeficiency virus was present in 46 (68.7%) patients. Early intensive care unit admission and ventilatorassociated pneumonia were independently associated with the in-hospital mortality. Conclusions: In this study we found a high mortality rate in TB patients requiring intensive care, especially in those with an early ICU admission.
Contido em BMC infectious diseases. London. Vol. 10, (2010), 7 p.
Assunto Cuidados intensivos
Mortalidade hospitalar
Tuberculose
Origem Estrangeiro
Tipo Artigo de periódico
URI http://hdl.handle.net/10183/21577
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